Registration Dossier
Registration Dossier
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EC number: 203-308-5 | CAS number: 105-55-5
Endpoint summary
Administrative data
Description of key information
Additional information
When release in water compartment
Due to its low octanol-water partition coefficient (log P=0.57) 1,3-diethyl-2-thiourea (DETU) is not expected to adsorb to sediment and will mainly be present in the aqueous phase. No specific study was performed to assess the hydrolysis of 1,3-diethyl-2-thiourea but it's well recognised that thioureas are stable in aqueous medium. This is confirmed by the hydrolysis data from analogous thioureas that are presented under a read-across approach.1,3-diethyl-2-thiourea is thus not expected to undergo hydrolysis in the environment. Furthermore, 1,3-diethyl-2-thiourea was shown to be not biodegradable with a ready biodegradability test.
When release in soil and sediment compartments
Due to a low log Kow, the substance should be characterised by a low potential of adsorption. This is supported with an estimated Koc value of 38.85 L/kg (Epiwin software). As a consequence, DETU will not persist in soil and sediment compartment because it will not adsorb on soil and sediment particules.
Bioaccumation potential
The partition coefficient of DETU was assessed by shake-flask method: log P = 0.57. This value indicates that DETU is characterised by a low potential of bioaccumulation.
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