Registration Dossier
Registration Dossier
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EC number: 249-044-4 | CAS number: 28472-97-1
Endpoint summary
Administrative data
Description of key information
Additional information
Diisodecyl azelate (CAS 28472-97-1) is readily biodegradable. Thus, Diisodecyl azelate will be rapidly removed from natural water compartments as well as from wastewater in sewage treatment plants. The substance has a log Koc > 5 indicating a potential to adsorb to soil and sediment particles. The estimated half time for the reaction with OH-radicals is 11.4 hours (24h day; OH-concentration: 0.5E+06 OH/cm3). However, photodegradation is not an important environmental fate process since the substance is not expected to evaporate into the atmosphere due to its very low vapor pressure of < 0.001 Pa at 20 °C. Due to its low water solubility (< 0.05 mg/L in aqua bidest), ready biodegradability and potential for adsorption to soil and sediment particles, only low concentrations of Diisodecyl azelate are expected to be released into the aquatic environment. The substance will be bioavailable to aquatic organisms mainly via feed and contact with suspended organic particles. Diisodecyl azelate is not bioaccumulative, based on the criteria given in Regulation (EC) No. 1907/2006, Annex XIII, 1.1.2 (BCF < 2000 L/kg). After uptake by fish species, extensive and fast biotransformation of the substance by carboxylesterases into Azelaic acid acid and the corresponding alcohol (Isodecanol) is expected. BCF/BAF values estimated with the BCFBAF v3.01 program, Arnot-Gobas model including biotransformation, also indicate that this substance will not be bioaccumulative (BCF/BAF: 0.9/1.1 L/kg).
In conclusion, Diisodecyl azelate is effectively removed from the environment by biotic and abiotic degradation processes. Due the low water solubility and high adsorption potential, the main route of exposure for aquatic organisms such as fish will be via food ingestion or contact with suspended solids. Ingested amounts of the substance in organisms are expected to be effectively metabolized to Azelaic acid and Isodecanol.
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