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EC number: 273-620-4
CAS number: 68990-67-0
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Quillaja saponaria, Rosaceae.
CHALLENGE TEST FOR POSITIVE CONTROL: Benzocaine (Cas No. 94-09-7)
Affected animals (%)
CHALLENGETEST FORTHE CONTROL GROUP
aim of the sensitization study was to assess the allergenic potential of
Quillaja Liquid Agri QL Agri 35-15 according to the test method
described by EV Buehler, (OECD 406).
Following dose levels were used: 100% w/v
solution of Quillaja Liquid Agri QL Agri 35-15 in the the induction
phase, 100% w/v solution of Quillaja Liquid Agri QL Agri 35-15 in the
Quillaja Liquid Agri QL Agri 35-15 didn't cause
skin sensitization on the Guinea pigs skin. Animals behaved normally and
their external appearance was not influenced by the treatment.
No data gaps were identified. The available data are adequate for
risk assessment and classification and labelling purposes.
In an OECD Guideline 406 study (Skin Sensitisation: Bühler Test),
no signs of skin sensitisation were observed.
According to the CLP Regulation (EU GHS Regulation (EC) No 1272/2008) no
classification and labelling is required for skin sensitisation of
Quillaja saponaria ext..
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