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EC number: 814-233-8 | CAS number: 444649-70-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- GLP compliance:
- not specified
- Type of method:
- effusion method: Knudsen cell
- Specific details on test material used for the study:
- Batch no.: lot # JBGJ0045R
Purity: 100% (UVCB) - Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0.01 Pa
- Remarks on result:
- other: calculated from the regression equation
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0.012 Pa
- Remarks on result:
- other: calculated from the regression equation
- Key result
- Temp.:
- 45 °C
- Vapour pressure:
- 0.028 Pa
- Key result
- Temp.:
- 60 °C
- Vapour pressure:
- 0.047 Pa
- Key result
- Temp.:
- 75 °C
- Vapour pressure:
- 0.077 Pa
- Conclusions:
- Under the study conditions, the vapour pressures of the test substance were dextrapolated using regression line and were determined to be 1.00E-02 and 1.24E-02 Pa at 20 and 25°C, respectively (Knudsen cell).
- Executive summary:
A study was conducted to determine the vapour pressure of the test substance according to OECD Guideline 104 and EU Method A.4 (Knudsen cell). The vapour pressure of the test substance was determined by the Knudsen cell effusion method. The test substance was weighed into the 4 Knudsen cells, which were set into vacuum chamber at 10E-05 Pa or lower followed by measurements at 30, 45, 60 and 75°C. The measurement at 30°C showed no significant weight loss. Therefore, this experiment was not included in the evaluation. The measured values for temperature and vapour pressure were evaluated as follows: 2.77E-02, 4.67E-02 and 7.71E-02 at 45, 60 and 75°C, respectively. Under the study conditions, the vapour pressures of the test substance were extrapolated using regression line and were determined to be 1.00E-02 and 1.24E-02 Pa at 20 and 25°C, respectively (Henke, 2015).
Reference
Table 1. Measured values for temperature and vapour pressure
Temperature (°C) | Vapour pressure (Pa) | Standart deviation (Pa) |
45 | 2.77E-02 | 1.97E-03 |
60 | 4.67E-02 | 2.60E-03 |
75 | 7.71E-02 | 1.11E-02 |
For the test substance, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:
20°C: 1.00E-02 Pa
25°C: 1.24E-02 Pa
The linear regression of log p vs. 1/T gave a correlation coefficient r of - 0.9999, showing good repeatability and precision. Therefore, the determination is considered as valid.
Description of key information
The vapour pressure was determined according to OECD Guideline 104 and EU Method A.4 (Knudsen cell) (Henke, 2015)
Key value for chemical safety assessment
- Vapour pressure:
- 0.028 Pa
- at the temperature of:
- 45 °C
Additional information
Vapour pressure at 45, 60 and 75°C = 2.77E-02, 4.67E-02 and 7.71E-02 Pa; and at 20 and 25°C (extrapolated using regression line) = 1.00E-02 and 1.24E-02 Pa
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