Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

In accordance with column 2, adaptation of Annex VIII (section 9.1.4) of Regulation (EC) No. 1907/2006, concerning toxicity testing to microorganisms "the study does not need to be conducted if there are mitigating factors indicating that microbial toxicity is unlikely to occur, for instance the substance is highly insoluble in water”.

Benzoic acid, 4-hydroxy-, C18-22-alkyl esters is highly insoluble in water (< 0.05 mg/L). The Guidance on information requirements and chemical safety assessment, Chapter R7.b (ECHA, 2012) states that once insoluble chemicals enter a standard STP, they will be extensively removed in the primary settling tank and fat trap and thus, only limited amounts will get in contact with activated sludge organisms. Therefore, the toxicity to microorganisms according to OECD Guidelines for Testing of Chemicals (1984) No 209 "Activated Sludge, Respiration Inhibition Test", Method C.11 of EEC Commission Directive 88/302/EEC was not conducted.