Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 610-977-0 | CAS number: 53201-62-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1998-04-21 to 1998-06-17
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: OECD study under GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
- Report date:
- 1998
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Version / remarks:
- 92/69/EWG, C.4-E (Geschl. Flasch.)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Hydrochinone-bis-p-hydroxybenzoate
- IUPAC Name:
- Hydrochinone-bis-p-hydroxybenzoate
- Details on test material:
- - Name of test material (as cited in study report): Hydrochinone-bis-p-hydroxybenzoate (OH-Dreikerner)
- Physical state: solid
- Storage condition of test material: in darkness at room temperature
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): sewage plant Groß-Zimmern, Germany
- Method of cultivation: The activated sludge used for this study was washed by centrifugation and the supernatant liquid phase was decanted. Two washing steps with tap water followed.
- Storage conditions: Aliquots of washed sludge suspension, corresponding to 4 g dry material per litre were mixed with test water and then aerated untiol use.
- Storage length: not given in the report
- Water filtered: yes
- Type and size of filter used, if any: cotton wool - Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 2 mg/L
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: KH2PO4 8.5 mg/l, K2HPO4 21.75 mg/l, Na2HPO4.2H2O 33.4 mg/l, NH4Cl 0.5 mg/l, MgSo4.7H2o 22.5 mg/l, CaCl2 27.5 mg/l, FeCl3.6H2O 0.25 mg/l, 36.4 mg/l CaCl2.2H2O
- Test temperature: 22 °C
- pH: 7.3 - 7.4
- Oxygen concentration of the test water: 8.75-8.90 mg O2/L
- pH adjusted: not given in the report
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: no
- Toxicity control: yes
- Procedure control: yes (Aniline)
TEST SYSTEM
- Culturing apparatus: Karlsruher flasks of 250 mL volume with glass stoppers
- Number of culture flasks/concentration: 16 bottles containing the test substance, 16 bottles with the reference substance, 16 bottles containing only inoculum and 8 bottles containing both the test and the reference substance
- Measuring equipment: oxygen electrode and pH-meter ECM Multi
SAMPLING
- Sampling frequency: Duplicate on days 0, 2, 5, 7, 12, 14, 21, 28
Reference substance
- Reference substance:
- aniline
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 12.1
- Sampling time:
- 28 d
- Details on results:
- Points of degradation plot (test substance):
-4.7 % degradation after 2 d
-1.3 % degradation after 5 d
-0.5 % degradation after 7 d
12.6 % degradation after 12 d
12.1 % degradation after 14 d
11.6 % degradation after 21 d
12.1 % degradation after 28 d
BOD5 / COD results
- Results with reference substance:
- Points of degradation plot (reference substance):
0.6 % degradation after 2 d
50.2 % degradation after 5 d
56.9 % degradation after 7 d
62.9 % degradation after 12 d
66.2 % degradation after 14 d
78.9 % degradation after 21 d
77.6 % degradation after 28 d
Any other information on results incl. tables
Hydroquinone-bis-p-hydroxybenzoate (OH-Dreikerner) is not redily biodegradable. The reference compound Aniline was sufficiently degraded to in the mean 66.2% afer 14 days and to 77.6% after 28 days, thus confirming the suitability of the used activated suludge inoculum. The biodegradation in the toxicity control containing both, the test substance and the reference compound Aniline showed a similar course over the 28 days of exposure as the procedure control containing the reference compound Aniline only.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- Hydroquinone-bis-p-hydroxybenzoate (OH-Dreikerner) is not redily biodegradable.
- Executive summary:
The test substance Hydroquinone-bis-p-hydroxybenzoate (OH-Dreikerner) was investigated for its ready biodegradability in a closed Bottle Test over a period of 28 days according to OECD Guideline 301D (1992) under GLP.
Under the test conditions the percentage biodegradation of Hydroquinone-bis-p-hydroxybenzoate (OH-Dreikerner) reached in the mean 12.1% after 28 days. The percentage biodegradation did not exceed 60% and can therefore not considered to be ready biodegradable. Both the refernce and the toxicity control were well within validity criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.