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EC number: 928-226-3 | CAS number: 1179884-99-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Testing was conducted between 14 August 2009 and 24 August 2009.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- A calculation was also performed using computer based specialist estimation software, WSKOW v 1.41, © 2000, U.S. Environmental Protection Agency.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Remarks:
- EXAMPLE: The determination was carried out using the flask method, Method A6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008.
Test material
- Reference substance name:
- PU Thickener
- IUPAC Name:
- PU Thickener
- Reference substance name:
- Octadecylamine, reaction products with 4,4’-methylene diphenyl diisocyanate
- IUPAC Name:
- Octadecylamine, reaction products with 4,4’-methylene diphenyl diisocyanate
- Test material form:
- other: solid
- Details on test material:
- Sponsor's identification: PU Thickener
Chemical name: Octadecylamine, reaction products with 4,4’-methylene diphenyl diisocyanate
Description : beige coloured solid
Batch number : VPSG011
Date received : 31 July 2009
Storage conditions: room temperature in the dark
The integrity of supplied data relating to the identity, purity and stability of the test material is the responsibility of the Sponsor
Constituent 1
Constituent 2
Results and discussion
Water solubility
- Water solubility:
- < 0.001 g/L
- Temp.:
- 20 °C
- pH:
- >= 5.6 - <= 6.6
- Details on results:
- Additionally, using an atom/fragment contribution method, the water solubility has been estimated to be less than or equal to 4.57 x 10-19 g/l at 25°C.
Any other information on results incl. tables
Results
Visual Estimation
The concentration (g/l) of test material in each sample, and appearance and pH of each sample, are shown in the following table:
Table 4.3
Sample Number |
Concentration (g/l) |
Appearance |
Solution pH |
1 |
2.50 x 10-3 |
Excess undissolved test material at the base of the flask, on the PTFE septum and at the surface of the solution. |
6.6 |
2 |
1.01 x 10-3 |
Excess undissolved test material at the surface of the solution and on the PTFE septum. |
6.0 |
3 |
5.2 x 10-4 |
Excess undissolved test material at the surface of the solution and on the PTFE septum. |
5.6 |
Overall: water solubility: less than 5.2 x 10-4g/l of solution.
Atom/Fragment Contribution
From information supplied by the Sponsor, the molecular weights of the test components were “788, 1038, 1307 + higher”. Upon review of this information, it was considered that the component with the lowest molecular weight would indicate a worst-case scenario for environmental assessment purposes.
The computer based estimate for the lowest molecular weight component of the test material indicated a water solubility value of 4.57 x 10-19g/l at 25°C. The calculation is illustrated in Attachment 2.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L) at the most
The water solubility of the test material has been determined to be less than 5.2 x 10-4 g/l of solution at 20.0 ± 0.5°C. Using an atom/fragment contribution method, the water solubility has been estimated to be less than or equal to 4.57 x 10-19 g/l at 25°C. - Executive summary:
Method
The determination was carried out using a procedure based on the flask method, Method A6 Water Solubility ofCommissionRegulation (EC) No 440/2008 of 30 May 2008.
The calculation was performed using computer based specialist estimation software, WSKOW v 1.41, © 2000, U.S. Environmental Protection Agency. ResultsVisual Estimation
Overall: water solubility: less than 5.2 x 10-4g/l of solution.Atom/Fragment Contribution
The computer based estimate for the lowest molecular weight component of the test material indicated a water solubility value of 4.57 x 10-19g/l at 25°C.
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