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EC number: 305-230-8 | CAS number: 94350-12-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Explosiveness
Administrative data
Link to relevant study record(s)
- Endpoint:
- explosiveness, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 05/02/2018 to 06/03/2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.14 (Explosive properties)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Key result
- Parameter:
- thermal sensitivity - Koenen test: diameter of the orifice plate
- Remarks on result:
- not thermal sensitive if heated under defined confinement
- Remarks:
- No explosion with the 3 tests using 6 mm orifice diameter and the 3 tests using the 2 mm orifice diameter.
- Key result
- Parameter:
- sensitiveness to impact: impact energy (J)
- Remarks on result:
- not sensitive to impact using an impact energy of 40 J
- Remarks:
- No reaction or decomposition observed for the 6 tests performed
- Key result
- Parameter:
- sensitiveness to friction: friction load (N)
- Remarks on result:
- not sensitive to friction using a friction load of 360 N
- Remarks:
- No reaction or decomposition during the 6 tests
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Saccharomyces Cerevisiae, Lysate was not explosive when exposed to thermal or mechanical stress (shock and friction) under the test conditions.
- Executive summary:
The determination of the explosive properties of Saccharomyces Cerevisiae, lysate was performed in accordance with EU method A.14 (Explosive properties) and in compliance with GLP.
The test substance was exposed to thermal and mechanical stress (shock and friction).
For the thermal sensitivity, a series of three tests with a 6.0 mm diameter orifice plate and a series of three tests with a 2.0 mm diameter orifice plate were performed on the sample using Koenen tube apparatus. The sample did not exhibit an explosion during any of the tests. The test result is therefore considered Negative (-) and the test item is not thermally sensitive.
A series of six tests was performed dropping the 10 kg mass from 0,4 m (40 J) on the sample using Bam Fallhammer apparatus for the sensitivity to shock. The sample was observed to exhibit no reaction at 40 J. The test result is therefore considered Negative (-) and the test item is not mechanical sensitive with respect to the shock.
To assess the sensitivity to the friction, a series of six tests was performed with a load of 360 N on the sample using Bam Friction apparatus. The sample was observed to exhibit no reaction at 360 N. The test result is therefore considered Negative (-) and the test item is not mechanical sensitive with respect to the friction.
In conclusion, Saccharomyces Cerevisiae, lysate was not explosive when exposed to thermal and mechanical stress (shock and friction) under the test conditions.
This explosive property study is classified as acceptable, and satisfies the guideline requirements of the EU method A.14.
Reference
Full test results (KOENEN TUBE)
Mass ofSample(g) |
OrificeDiameter(mm) |
Time to First Ignition (s) |
Explosion (X /Y)* |
16.7 |
6 |
31 |
X |
16.7 |
6 |
26 |
X |
16.7 |
6 |
29 |
X |
16.7 |
2 |
26 |
X |
16.7 |
2 |
22 |
X |
16.7 |
2 |
21 |
X |
* ‘Y’ denotes 3 or more fragments.
‘X’ denotes fewer than 3 fragments.
Full test results (BAM FALLHAMMER)
Mass (kg) |
Height (m) |
Energy (J) |
Test number and results*(X /Y) |
Comments |
|||||
1 |
2 |
3 |
4 |
5 |
6 |
||||
10 |
0.4 |
40 |
X |
X |
X |
X |
X |
X |
No reaction observed |
* ‘Y’ denotes an explosion (includes crackling, sparking, inflammation).
‘X’ denotes no reaction or decomposition (change incolour).
Full test results (BAM FRICTION)
Mass (kg) |
Load (N) |
Test number and results*(X /Y) |
Comments |
|||||
1 |
2 |
3 |
4 |
5 |
6 |
|||
8.34 |
360 |
X |
X |
X |
X |
X |
X |
No reaction observed |
* ‘Y’ denotes an explosion (includes crackling, sparking, inflammation).
‘X’ denotes no reaction or decomposition (change incolour).
Description of key information
Saccharomyces Cerevisiae, Lysate was not explosive when exposed to thermal or mechanical stress (shock and friction) under the test conditions of EU method A.14.
Key value for chemical safety assessment
- Explosiveness:
- non explosive
Additional information
The determination of the explosive properties of Saccharomyces Cerevisiae, lysate was performed in accordance with EU method A.14 (Explosive properties) and in compliance with GLP.
The test substance was exposed to thermal and mechanical stress (shock and friction).
For the thermal sensitivity, a series of three tests with a 6.0 mm diameter orifice plate and a series of three tests with a 2.0 mm diameter orifice plate were performed on the sample using Koenen tube apparatus. The sample did not exhibit an explosion during any of the tests. The test result is therefore considered Negative (-) and the test item is not thermally sensitive.
A series of six tests was performed dropping the 10 kg mass from 0,4 m (40 J) on the sample using Bam Fallhammer apparatus for the sensitivity to shock. The sample was observed to exhibit no reaction at 40 J. The test result is therefore considered Negative (-) and the test item is not mechanical sensitive with respect to the shock.
To assess the sensitivity to the friction, a series of six tests was performed with a load of 360 N on the sample using Bam Friction apparatus. The sample was observed to exhibit no reaction at 360 N. The test result is therefore considered Negative (-) and the test item is not mechanical sensitive with respect to the friction.
In conclusion, Saccharomyces Cerevisiae, lysate was not explosive when exposed to thermal and mechanical stress (shock and friction) under the test conditions.
Justification for classification or non-classification
The test substance was exposed to thermal and mechanical stress (shock and friction) under the consitions of the EU Method A.14 and it did not exhibit an explosion during any of these tests.
The test item is not thermally sensitive, it is not mechanical sensitive with respect to the shock and it is not mechanical sensitive with respect to the friction.
In conclusion, Saccharomyces Cerevisiae, lysate was not explosive when exposed to thermal and mechanical stress (shock and friction) under the test conditions.
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