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EC number: 268-799-0 | CAS number: 68140-48-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16th July 1990 to 13th August 1990
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- The sealed vessel test is a CO2 production test based on OECD Guideline 301B. The test system is closed and is therefore suitable for the examination of volatile materials.
- Principles of method if other than guideline:
- The sealed vessel test is a CO2 production test based on OECD Guideline 301B. The test system is closed and is therefore suitable for the examination of volatile materials.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 1-[2,3-dihydro-1,1,2,6-tetramethyl-3-(1-methylethyl)-1H-inden-5-yl]ethan-1-one
- EC Number:
- 268-799-0
- EC Name:
- 1-[2,3-dihydro-1,1,2,6-tetramethyl-3-(1-methylethyl)-1H-inden-5-yl]ethan-1-one
- Cas Number:
- 68140-48-7
- Molecular formula:
- C18H26O
- IUPAC Name:
- 1-[1,1,2,6-tetramethyl-3-(propan-2-yl)-2,3-dihydro-1H-inden-5-yl]ethan-1-one
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- TRASEOLIDE :
Lot No. / Sample Code : R485
Purity : 97% (total of Isomers); 84% (Main Peak)
Date of Expiry : Not known
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- The inoculum was 10% by volume of activated sludge plant secondary effluent, filtered through a Whatman filter paper (541) to remove coarse particulate matter. The level of dissolved inorganic carbon was reduced by sparging the filtered effluent with nitrogen after prior adjustment of the pH to 6.5.
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 10 mg/L
- Based on:
- other: Nominal concentration of Organic Carbon
Parameter followed for biodegradation estimationopen allclose all
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Parameter followed for biodegradation estimation:
- inorg. C analysis
- Remarks:
- Dissolved Inorganic Carbon
- Details on study design:
- The test used was the sealed vessel test which is suitable for determining the ready and ultimate biodegradability of organic substances. The test was conducted in 160 mL vessels (hypovials) containing 100 mL mineral salts medium inoculated with secondary effluent and the respective test or reference substance. Multiple vessels are prepared per substance sealed with butyl rubber septa and an aluminium crimp seal. The headspace in each vessel has a volume of 60 mL and, when filled with air, contains approximately 6 times the mass of oxygen required for the complete oxidation of the test item.
The sealed vessels are incubated at 20 °C on a rotary shaker. At intervals during the 28 day test period (Day 3, 7, 10, 14, 17, 21, 24 and 28) a vessel is removed and concentration of carbon dioxide in the headspace gas determined. The seal is then broken and the concentration of inorganic carbon in the test medium is also determined. The total inorganic carbon in the vessel is calculated and corrected by subtracting the total inorganic carbon produced in the Control. The Control vessels were identical to the test vessels except for the omission of the test substance. From a knowledge of the initial organic carbon concentration added as a test substance, the extent of mineralisation can be determined.
Results and discussion
% Degradation
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- -6.6
- Sampling time:
- 28 d
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- TRASEOLIDE was not found to be Readily Biodegradable under the test conditions.
Biodegradation, based on evolved headspace CO2 and dissolved inorganic carbon was effectively zero on Day 28 (actual determined vs Control = - 6.6% (95% confidence interval : -9.0 to -4.2%).
Day % Biodegradation
3 9.3
7 -3.5
10 -7.6
14 -0.1
17 -1.1
21 3.3
24 0.0
28 -6.6 - Executive summary:
TRASEOLIDE was not found to be Readily Biodegradable under the test conditions.
Biodegradation, based on evolved headspace CO2 and dissolved inorganic carbon was effectively zero on Day 28 (actual determined vs Control = - 6.6% (95% confidence interval : -9.0 to -4.2%).
Day % Biodegradation
3 9.3
7 -3.5
10 -7.6
14 -0.1
17 -1.1
21 3.3
24 0.0
28 -6.6
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