Registration Dossier
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EC number: 216-823-5 | CAS number: 1675-54-3
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Hydrolysis rate: -5.92 [1/hr] at 25 °C independent of pH.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 117 h
- at the temperature of:
- 25 °C
Additional information
Hydrolysis was investigated following the OECD 111 guideline at 1.93 mg/l and 50°C in buffered solutions of pH 4,7, and 9. Samples were taken over 24 hrs. Based on the experimental data and information on other epoxides the author suggest that hydrolysis is independent from pH and the values determined at pH 4, 7, and 9 can be combined to calculate a hydrolysis half-life of 117 hrs at 25 °C (95% confidence range: 68–204 h). These findings are supported by the hydrolysis rate observed in an OECD 301F ready biodegradation study with a half-live of 12.3 days at 20 °C. Products of hydrolysis were identified as mono-diol and the di-diol from reaction of the two epoxy groups.
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