Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

  • EC / List name: Dichloro(dimethyl)silane
  • IUPAC name: dichlorodimethylsilane
  • Other names
EC / List no.:
200-901-0
CAS no.:
75-78-5
Index number:
014-003-00-X
Molecular formula:
C2H6Cl2Si
SMILES:
C[Si](C)(Cl)Cl
InChI:
InChI=1S/C2H6Cl2Si/c1-5(2,3)4/h1-2H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
30
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is a highly flammable liquid and vapour, causes serious eye irritation, causes skin irritation and may cause respiratory irritation.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes severe skin burns and eye damage, is toxic if inhaled and is harmful if swallowed.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye damage.

Breakdown of all 3379 C&L notifications submitted to ECHA

Flam. Liq. 2 H225 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
Eye Irrit. 2 H319 Harmonised Classification
Skin Irrit. 2 H315 Harmonised Classification
Acute Tox. 3 H331
Acute Tox. 4 H302
Skin Corr. 1A H314
Eye Dam. 1 H318
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 93 active registrations under REACH, 1 Joint Submission(s) and 1 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 100 000 - 1 000 000 tonnes per year.

This substance is used in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

ECHA has no public registered data indicating whether or into which articles the substance might have been processed.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

ECHA has no public registered data on the types of manufacture using this substance.

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

This substance is used in the following products: cosmetics and personal care products, polymers, adhesives and sealants, coating products, non-metal-surface treatment products, heat transfer fluids, inks and toners, pH regulators and water treatment products, laboratory chemicals, leather treatment products, lubricants and greases, pharmaceuticals, polishes and waxes, textile treatment products and dyes, washing & cleaning products and water treatment chemicals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, mixing in open batch processes, transfer of substance into small containers, laboratory work and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: semiconductors, non-metal-surface treatment products and textile treatment products and dyes. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used for the manufacture of: chemicals, electrical, electronic and optical equipment and mineral products (e.g. plasters, cement).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure and closed, continuous processes with occasional controlled exposure.

Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, as processing aid, in the production of articles and as processing aid.

This substance is used in the following activities or processes at workplace: transfer of chemicals at dedicated facilities and closed processes with no likelihood of exposure.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: take actions to prevent static discharges; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. If swallowed: rinse mouth. Do not induce vomiting. If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. Immediately call a poison center or doctor/physician. If eye irritation persists get medical advice/attention. Call a poison center or doctor/physician.

Storage statements

Store this substance in a closed container; in a well-ventilated place and Keeping it cool; in a well-ventilated place and keeping container tightly closed.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • ABC/Allied Pressroom Products (Europe) Limited, ul. Zupnicza 17 03-821 Warsaw Poland
  • ARCHROMA IBÉRICA, S.L., ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BRB International B.V., Branskamp 12 6014 CB Ittervoort Netherlands
  • BYK-Chemie GmbH, Abelstr. 45 DE-46483 Wesel Germany
  • Cabot Performance Materials Belgium SPRL, rue Prévochamps, 78 4860 Pepinster Belgium
  • Caplinq Europe B.V., De Trompet 1126 1967 DA Heemskerk Netherlands
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Guangzhou Jinggui New Materials Co., Ltd.), Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(HOSHINE SILICON INDUSTRY CO., LTD), Room 002, Regus Harcourt Centre D02 HW77, D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED(Zaoyang Jinpeng Chemical Co., Ltd), Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Solutions Limited, 27 Old Gloucester Street WC1N 3AX London United Kingdom
  • Chemservice GmbH - (SA3Q), Herrnsheimer Hauptstrasse 1b 67550 Worms Germany
  • CHT Germany GmbH, Bismarckstr. 102 72072 Tuebingen Germany
  • CS Regulatory Ltd 1L-24, The Old Courthouse St Peters Churchyard DE1 1NN Derby United Kingdom
  • Cyber Clean Europe GmbH, Enzianstraße 6 82319 Starnberg Germany
  • Dow Silicones Belgium SPRL, PSRC - Rue Jules Bordet Zone industrielle C 7180 Seneffe Belgium
  • Dow Silicones Belgium SPRL OR-1, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • Dow Silicones Belgium SPRL OR-2, PSRC - rue Jules Bordet Parc industriel C 7180 Seneffe Belgium
  • Dow Silicones Belgium SPRL OR-3, PSRC - Rue Jules Bordet Zone industrielle C 7180 Seneffe Belgium
  • Dow Silicones UK Limited, PSRC - Cardiff Road CF632YL Barry, South Glamorgan Wales United Kingdom
  • Elementis UK Ltd., Caroline House 55 - 57 High Holborn WC1V 6DX London United Kingdom
  • Elementis UK Ltd. OR 1, Caroline House 55 - 57 High Holborn WC1V 6DX London United Kingdom
  • ELKEM SILICONES FRANCE S.A.S., Immeuble DANICA 21, Avenue Georges Pompidou 69003 Lyon France
  • Evonik Degussa GmbH, Rellinghauser Strasse 1 - 11 C-ES 45128 Essen North Rhine-Westfalia Germany
  • Evonik Degussa GmbH - OR3, Rellinghauser Straße 1 - 11 45128 Essen Germany
  • Evonik Italia S.r.l., Via Falconera, 7 26025 Pandino (CR) Italy
  • Evonik Nutrition & Care GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Evonik Nutrition & Care GmbH - OR2, Goldschmidtstrasse 100 45127 Essen Germany
  • Evonik Resource Efficiency GmbH, Rellinghauser Strasse 1-11 45128 Essen Germany
  • Evonik Resource Efficiency GmbH – M02, Rellinghauser Straße 1-11 45128 Essen Nordrhein-Westfalen Germany
  • FSB Specialty Chemicals, vijverbroekstraat 13 6015aa neeritter Netherlands
  • GRACE GmbH, In der Hollerhecke 1 67545 Worms Germany
  • GW United Chemicals GmbH, Martin-Behaim-Str. 2 63263 Neu-Isenburg Germany
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • Huntsman Textile Effects (Germany) GmbH, Rehlinger Str. 1 D-86462 Langweid a.Lech Germany
  • Innospec Limited (OR1), Innospec Manufacturing Park Oil Sites Road CH65 4EY Ellesmere Port Cheshire United Kingdom
  • KCC Europe GmbH, Hansaring 61 50670 Köln Germany
  • knoell Germany – OR – B10, Konrad-Zuse-Ring 25 68163 Mannheim Germany
  • Kurt Obermeier GmbH & Co. KG, Berghäuser Straße 70 57319 Bad Berleburg Germany
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • Livchem Logistics GmbH, Fritz-Klatte-Strasse 8 D-65933 Frankfurt Germany
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Europe Coordination Center BVBA 01, Chaussee De Wavre, 1945 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 02 , Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 05, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 06, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 16, Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol France SAS, 25 Quai de France 76100 ROUEN France
  • Merck Performance Materials GmbH, Rheingaustrasse 190-196 65203 Wiesbaden Germany
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • MÜNZING CHEMIE GMBH as Only Representative for Ultra Additives LLC dba Munzing, Münzingstr. 2 74232 Abstatt Germany
  • Nalco Limited, P.O. Box 11, Winnington Avenue, CW8 4DX Northwich, Cheshire United Kingdom
  • Nitrochemie Aschau GmbH, Liebigstrasse 17 84544 Aschau am Inn Germany
  • Nouryon Chemicals NV/SA, Parc Industriel de Ghlin Zone A 7011 Ghlin Mons Belgium
  • Nouryon Functional Chemicals B.V., Velperweg 76 6824 BM Arnhem Netherlands
  • Onichem International B.V., Stadionweg 57A 3077 AS Rotterdam Netherlands
  • Penman Consulting bvba 05, Avenue des Arts 10 B-1210 Brussels Belgium
  • PPG Europe B.V. - OR1, Amsterdamseweg 14 1422 AD Uithoorn Netherlands
  • Red Orchid Consulting Oy Ltd, Viherkallionkuja 3 I 59 02710 Espoo Finland
  • Rudolf GmbH, Altvaterstr. 58 - 64 82538 Geretsried Germany
  • RUTESIL SP. Z O.O., 1 MAJA 11/55, 37-310, N/A NOWA SARZYNA Poland
  • Soudal, Everdongenlaan 18-20 2300 Turnhout Belgium
  • Specialty Electronic Materials Belgium, BVBA, Sneeuwbeslaan 20 / Pb10 B-2610 Wilrijk Belgium
  • Specialty Electronic Materials Netherlands B.V. OR-1, Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • Specialty Electronic Materials Netherlands B.V. OR-2, Herbert H. Dowweg 5 4542NM Hoek Netherlands
  • Sustainability Support Services (Europe) AB, Markaskälsvägen 6 22647 Lund Sweden
  • TOKUYAMA EUROPE GMBH, Am Gierath 20A 40885 Ratingen Germany
  • TRECO SRL, Via Romagna 8 20098 SAN GIULIANO MILANESE MILANO Italy
  • Unilever Nederlands Services BV 06, Nassaukade 3 3071 JL Rotterdam Netherlands
  • UNION QUIMICO FARMACÉUTICA S.A., Mallorca 262 08008 Barcelona Barcelona Spain
  • UNISIL Hungary Szilikongyártó Kft., Sárkány u. 7-9. 5.em. 3. 1089 Budapest Hungary
  • Wacker Chemie AG, Hanns-Seidel-Platz 4 81737 Muenchen Germany
  • Wacker Chemie AG (OR_WCC), Johannes-Hess-Strasse 24 84489 Burghausen Germany
  • Wacker Chemie AG (OR_WCH_ZJG), Johannes-Hess-Strasse 24 84489 Burghausen Bavaria Germany
  • Wacker Chemie AG (OR_WMC), Johannes-Hess-Strasse 24 84489 Burghausen Bavaria Germany
  • Wilkinson Sword GmbH, Schuetzenstr. 110 42659 Solingen NRW Germany
  • WSP UK Ltd (OR1), The Victoria 150-182 The Quays M50 3SP Salford Greater Manchester United Kingdom
  • [Confidential], [Confidential]
  • Henkel CR spol.s r.o., U Pruhonu 10 17004 Praha 7 Czech Republic
  • Henkel Electronic Materials (Belgium) N.V., Nijverheidsstraat 7 2260 Westerlo Belgium
  • Henkel Nederland B.V., Brugwal 11 3432 NZ Nieuwegein Netherlands
  • The Bergquist Company GmbH, Verbindungsweg 42 25469 Halstenbek Germany

Other names

  • -
  • 13407_75-78-5
  • chlorosilane
  • Dichloro(dimethyl)silane
  • dichloro(dimethyl)silane (DDS)
  • Dichlorodimethylsilane
  • DIMETHYLDICHLOROSILANE
  • Dimethyldichlorsilan
  • Dimetyldichlorosilane
  • DMS
  • Dichloro(dimethyl)silane
  • dimethyldichlorosilane
  • DCDMS
  • Di, C-322; DIME-DICL-SILAN; SC3002
  • DIMETHYLDICHLOROSILANE
  • dimethylpolysiloxane
  • DOW CORNING(R) 1-2244 INT
  • DOW CORNING(R) Z-0404 INT
  • DOW CORNING(R) Z-1219
  • Dow Corning(R) Z-1219 (dimethyldichlorosilane)
  • KA-22
  • SC3100Z
  • SF2901E
  • SF5100PFK010
  • SF5400P
  • SF9902E
  • SF9905E
  • SF9912E
  • SH0005U
  • SH0007B
  • SH0030U
  • SH1660U
  • SH3055B
  • SH5060U
  • SH5070U
  • SH5180U
  • SH5860U
  • SH6580U
  • SM4110P
  • SM4115P
  • dimethyldichlorosilane

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 3 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Not specified (100%) [1]
C Substance type
Organic (100%) [1]

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 8 studies submitted
  • 1 study processed
R Melting / freezing point
-76.1 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 7
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-76.1 °C

Boiling point

Study results
  • 11 studies submitted
  • 1 study processed
R Boiling point
70.2 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 9
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
70.2 °C

Density

Study results
  • 5 studies submitted
  • 1 study processed
R Density
1.1 g/cm³ @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 10 studies submitted
  • 1 study processed
R Vapour pressure
14.626 - 50.798 kPa @ 20 - 50 °C [4]

Type of Study provided
Studies with data
Key study 1
Supporting study 3 2 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
14.6 kPa @ 20 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1 1
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Water solubility

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 9 studies submitted
  • 1 study processed
R Flash point
1 - 79 °C @ 101.3 kPa [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 7
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
1 °C

Auto flammability

Study results
  • 6 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
425 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
425 °C

Flammability

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Highly flammable (100%)

Explosiveness

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 3 studies submitted
  • 1 study processed
R kinematic viscosity (in mm²/s)
0.35 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Static viscosity at 20 °C
0.35 mm²/s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Hydrolysis

Study results
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study 2 6
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Under test conditions no biodegradation observed (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Under test conditions no biodegradation observed (100%)

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0 Pa.m³.mol-1 @ 12 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater No hazard identified (1)
Intermittent releases (freshwater) No hazard identified (1)
Marine water No hazard identified (1)
Intermittent releases (marine water) No hazard identified (1)
Sewage treatment plant (STP) 6.9 mg/L (1)
Sediment (freshwater) 5.54 mg/kg sediment dw (1)
Sediment (marine water) 554 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 346 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 126 mg/L [1]
NOEC (4 days) 126 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (48 h) 117 mg/L [1]
NOEC (48 h) 117 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (21 days) 100 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (72 h) 118 mg/L [1]
NOEC (72 h) 118 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC10 (3 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 49.4 mg/m³ developmental toxicity / teratogenicity
Acute /short term: (DNEL) 49.4 mg/m³ developmental toxicity / teratogenicity
Local Effects
Long-term: (DNEL) 14.2 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 14.2 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 7 mg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: (DNEL) 7 mg/kg bw/day developmental toxicity / teratogenicity
Local Effects
Long-term: Medium hazard (no threshold derived)
Acute /short term: Medium hazard (no threshold derived)
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.7 mg/m³ developmental toxicity / teratogenicity
Acute /short term: (DNEL) 8.7 mg/m³ developmental toxicity / teratogenicity
Local Effects
Long-term: (DNEL) 4.8 mg/m³ irritation (respiratory tract)
Acute /short term: (DNEL) 4.8 mg/m³ irritation (respiratory tract)
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 2.5 mg/kg bw/day developmental toxicity / teratogenicity
Acute /short term: (DNEL) 2.5 mg/kg bw/day developmental toxicity / teratogenicity
EYE Exposure
Medium hazard (no threshold derived)

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation potential:
No bioaccumulation potential

Acute toxicity

Study results
oral
  • 3 studies submitted
  • 1 study processed
P/RResults
LD50 595 mg/kg bw (rat) [1]
M/CInterpretations of results
Harmful [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 4 studies submitted
  • 1 study processed
P/RResults
LC50 (60 min) 2 092 ppm (rat) [1]
M/CInterpretations of results
Harmful [1]

inhalation
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

dermal
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 595 mg/kg bw
Inhalation route:
Adverse effect observed LC50 5 521 mg/m³

Irritation / corrosion

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
No study available
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No study available
Respiratory sensitisation
No study available

Repeated dose toxicity

Study results
Study data: oral
  • 1 study submitted
  • 1 study processed
P/RResults
NOAEL (rat): 250 mg/kg bw/day [1]

Type of Study provided
Study data: oral
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study 1
Supporting study 1 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 250 mg/kg bw/day (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Study data: developmental
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 500 mg/kg bw/day (subacute, rat)
Effect on developmental toxicity
Oral route:
Adverse effect observed NOAEL 250 mg/kg bw/day (subacute, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant