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EC number: 217-157-8 | CAS number: 1758-73-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (28 d) ≥ 100 mg/L for activated sludge microorganisms (OECD 301C)
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100 mg/L
Additional information
Two studies are available investigating the effects of
aminoiminomethanesulphinic acid (CAS No. 1758-73-2) to
microorganisms.The key study investigated the effects on microorganisms
in a biodegradation study according to OECD 301C under GLP conditions
(Ministry of Economy, Trade and Industry, Japan, 1991). The study was
performed with a mixture of activated sludge from STP with freshwater
from rivers and lakes, marine water and marine sediment. No inhibition
of biodegradation was observed after 28 d. The test concentration from a
biodegradation study which indicated that the test substance is readily
biodegradable can be used to derive a NOEC for this endpoint as stated
in the ECHA Guidance R.7b (ECHA, 2012). Therefore, the test item
concentration of 100 mg/L can be used as NOEC value for the toxicity to
activated sludge microorganisms. Thus a NOEC (28 d) of ≥ 100 mg/L
resulted.
An additional study confirmed the low toxicity
ofaminoiminomethanesulphinic acid to microorganisms (Coenen, 1988). The
inhibition of cell multiplication was investigated in a study according
to NEN 6509. Twelve concentrations up to 1000 mg/L (nominal) were
tested. After incubation of 18 h a toxicity threshold value of 538 mg/L
was derived . The toxicity threshold is not an accepted endpoint for the
risk assessment but it indicated a low toxicity of the test substance to
microorganisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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