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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The aquatic toxicity of beta-mannosidase has not been tested, however a similar enzyme - alpha-amylase - has been tested in both daphnia and algae. 


Due to the simmilarity of the two enzymes similar results are expected for beta-mannosidase. In addition, since alpha-amylase has a high toxicity towards aquatic organisms, it has been chosen as a worst-case scenario.


Toxicity to aquatic invertebrates: The 48 h EC50 value for alpha-amylase with Daphnia magna is 1758 mg enzyme concentrate dry matter/L corresponding to 212 mg active enzyme protein/L.


Toxicity to algae and cyanobacteria: Alpha-amylase, batch PPA4048 was inhibitory to the growth of Desmodesmus subspicatus. The ErC50 (24-72h) was 43.1 mg enzyme concentrate dry matter/L 5.2 mg active enzyme protein/L. NOEC for the 24 -72 hour growth rate was 22 mg enzyme concentrate dry matter/L. EbC50 (72h) was 21.1 mg enzyme concentrate dry matter/L.

Additional information