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EC number: 287-643-2 | CAS number: 85566-32-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Type: Activated Sludge
Source: Cambridge Sewage Treatment Works, Cowley Road
Sludge pre-treatment: Sieved to 850μm to remove coarse particulates, settled and centrifuged at approximately 4000rpm for approximately 5-10 minutes. The supernatant was discarded and the sludge pellet re-suspended in mineral media. The sludge was centrifuged again at 4000rpm for approximately 5-10 minutes and then the supernatant discarded. The resulting sludge pellet was homogenised thoroughly by mechanical stirring. Dry sludge solids content determined on the homogenised pellet.
Dry sludge solids: 4.79%
Volume of mineral medium: 1.5L per bioreactor
Dry sludge solids in test: 0.03g/L - Duration of test (contact time):
- 28 d
- Initial conc.:
- 61.3 mg/L
- Based on:
- TOC
- Remarks:
- Test 1
- Initial conc.:
- 61.2 mg/L
- Based on:
- TOC
- Remarks:
- Test 2
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- Conical flasks of nominal volume 2000ml were filled with 1500mL of inoculated mineral medium. The blanks, reference and test bottles were set up in duplicate, with a single replicate for the toxicity control. Test and reference materials were added to appropriate bottles to a final concentration of 20 mg Carbon/L. Atmospheric air was pumped into the test system and scrubbed clean of carbon dioxide by passing over soda lime. The air continued into the test vessel where it collects any evolved carbon dioxide before moving into the carbon dioxide traps, each containing 200 mL of 0.05M sodium hydroxide solution. The test solutions were stirred and maintained between 22.0 – 23.8°C over the duration of the study.
- Reference substance:
- acetic acid, sodium salt
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 50
- Sampling time:
- 7 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 90
- Sampling time:
- 14 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 101
- Sampling time:
- 23 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 105
- Sampling time:
- 28 d
- Results with reference substance:
- A maximum average value of 89% degradation of the sodium acetate was achieved on day 29.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The test substance was readily biodegradable under the conditions of this test.
- Executive summary:
The ready biodegradation of Fatty acids, C16-18, reaction products with ethanolamine was evaluated during a GLP-compliant study conducted according to the OECD Testing Guideline 301B.
The test substance gave a positive result (>60% degradation relative to the ThCO2 value) with a maximum of 116% recorded on day 29 (values in excess of 100% may be a result of analytical variation). It may therefore be concluded that there is a potential for biodegradation under environmental conditions.
The inoculum blank should not normally produce more than 70 mg/L CO2 (19.1 mg/L C) for the test to be valid. A value of 28.1 mg/L CO2 (7.7 mg/L C) was recorded.
The guideline requires that the reference material degrades by at least 60% of its ThCO2 value, a maximum average value of 89% degradation of the sodium acetate was achieved on day 29.
The test protocol requires that a 10-day window is applied to the degradation results (60% degradation to be reached within 10 days of 10% of the theoretical carbon dioxide produced). Fatty acids, C16-18, reaction products with ethanolamine reached 69% degradation within 9 days, therefore the 10-day window was achieved.
Mean reference degradation also achieved 62% within 9 days, passing the 10-day window.
Fatty acids, C16-18, reaction products with ethanolamine was insoluble in water at the required level for this test, therefore measured quantities of the test item were added directly into the test bioreactors.
The final conclusion of this study is that Fatty acids, C16-18, reaction products with ethanolamine was readily biodegradable under the conditions of this test.
Reference
Description of key information
The ready biodegradation of Fatty acids, C16-18, reaction products with ethanolamine was evaluated during a GLP-compliant study conducted according to the OECD Testing Guideline 301B.
The test substance gave a positive result (>60% degradation relative to the ThCO2 value) with a maximum of 116% recorded on day 29 (values in excess of 100% may be a result of analytical variation). It may therefore be concluded that there is a potential for biodegradation under environmental conditions.
The inoculum blank should not normally produce more than 70 mg/L CO2 (19.1 mg/L C) for the test to be valid. A value of 28.1 mg/L CO2 (7.7 mg/L C) was recorded.
The guideline requires that the reference material degrades by at least 60% of its ThCO2 value, a maximum average value of 89% degradation of the sodium acetate was achieved on day 29.
The test protocol requires that a 10-day window is applied to the degradation results (60% degradation to be reached within 10 days of 10% of the theoretical carbon dioxide produced). Fatty acids, C16-18, reaction products with ethanolamine reached 69% degradation within 9 days, therefore the 10-day window was achieved.
Mean reference degradation also achieved 62% within 9 days, passing the 10-day window.
Fatty acids, C16-18, reaction products with ethanolamine was insoluble in water at the required level for this test, therefore measured quantities of the test item were added directly into the test bioreactors.
The final conclusion of this study is that Fatty acids, C16-18, reaction products with ethanolamine was readily biodegradable under the conditions of this test.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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