Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 602-927-1 | CAS number: 123312-89-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13 Nov 1992 to 16 Mar 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- May 1981
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Version / remarks:
- September 1984
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- -0.18
- Temp.:
- 25 °C
- pH:
- 7.1
- Remarks on result:
- other: S.D.: 0.004
- Conclusions:
- The octanol-water partition coefficient (Log Pow) of the test substance at 25 °C was -0.18.
- Executive summary:
The octanol-water partition coefficient (Log Pow) of the test substance was determined based on the flask method in accordance with OECD TG 107 and in compliance with GLP. The octanol-water partition coefficient (Log Pow) of test substance at approximately 25 °C was -0.18.
Reference
Table: Partition Coefficient Results
Sample number |
1 |
2 |
3 |
4 |
5 |
6 |
weight of test substance / mg |
2.0774 |
2.0774 |
4.1548 |
4.1548 |
8.3096 |
8.3096 |
volume of octanol / mL Volume of water / mL |
10.0 20.0 |
10.0 20.0 |
20.0 20.0 |
20.0 20.0 |
40.0 20.0 |
40.0 20.0 |
concentration of the substance in the octanol phase / (mg / L) Average of 3 values |
50.574 50.411 50.445 50.477 |
50.073 49.943 50.247 50.088 |
80.604 80.479 81.087 80.723 |
81.158 81.169 81.392 81.240 |
117.590 117.614 117.139 117.448 |
114.557 114.904 115.212 114.891 |
concentration of the substance in the aqueous phase / (mg/L) Average of 3 values pH of aqueous phase |
76.398 76.830 76.620 76.616 7.11 |
76.863 76.894 76.685 76.814 7.13 |
123.742 123.595 123.178 123.505 6.91 |
122.342 122.969 123.279 122.863 7.06 |
178.525 179.255 178.484 178.755 7.09 |
178.352 178.363 178.467 178.394 7.08 |
amount of the substance in the octanol phase / mg amount of the substance in the aqueous phase / mg total recovered amount of substance / mg |
0.5048
1.5323
2.0371 |
0.5009
1.5363
4.0846 |
1.6145
2.4701
4.0846 |
1.6248
2.4573
4.0821 |
4.6979
3.5751
8.2730 |
4.5956
3.5679
8.1635 |
recovery / % |
98 |
98 |
98 |
98 |
100 |
98 |
Pow |
0.6588 |
0.6521 |
0.6536 |
0.6612 |
0.6570 |
0.6440 |
average Pow |
0.6555 |
0.6574 |
0.6505 |
|||
average Pow ± S.D. |
0.56 ± (0.006) |
|||||
log Pow |
-0.1812 |
-0.1857 |
-0.1847 |
-0.1797 |
-0.1824 |
-0.1911 |
Average log Pow |
-0.1835 |
-0.1822 |
-0.1868 |
|||
Average log Pow ± S.D. |
-0.18 ± (0.004) |
Description of key information
Log Pow = -0.18 at 25 °C, OECD 107, flask method, Rodler 1993
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.18
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.