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Diss Factsheets
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EC number: 208-536-9 | CAS number: 532-40-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
According to Article 13 of Regulation (EC) No 1907/2006 "General Requirements for Generation of Information on Intrinsic Properties of substances", information on intrinsic properties of substances may be generated by means other than tests e.g. from information from structurally related substances (grouping or read-across), provided that conditions set out in Annex XI are met. In Annex XI, "General rules for adaptation of this standard testing regime set out in Annexes VII to X”, it is stated that “substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or ‘category’ of substances. This avoids the need to test every substance for every endpoint”.
A read-across approach was applied to this substance and data was compiled from a representative source substance to avoid unnecessary animal testing. The target substance will be classified and labelled on this basis.
Environmental fate and pathways
Hydrolysis
50% recovery after 30 d (pH 9.0) and 40 d (pH 4.6 and 6.9) at 25 °C (OECD 111); read-across
Degradation
Not readily biodegradable (39% ThODNH4/25% ThODNO3); read-across
Bioaccumulation
log Kow = -4.7 at 20 °C (EU Method A.8., Calculation method)
log D = -3.3 to -8.0 (pH 0 – 14, SPARC v4.6)
Aquatic acute toxicity
Fish
LC50 (96 h) > 100 mg/L (nominal, OECD 203, D. rerio); read-across
Aquatic invertebrates
EC50 (48 h) > 100 mg/L (nominal, OECD 202, D. magna); read-across
Aquatic algae
ErC50 (72 h) > 100 mg/L (geometric mean measured, OECD 201, P. subcapitata); read-across
Aquatic chronic toxicity
Aquatic algae
ErC10 (72 h) > 100 mg/L (geometric mean measured, OECD 201, P. subcapitata); read-across
Conclusion on CLP
Based on the compiled data above, no short-term toxicity to aquatic organisms of all three trophic levels (fish, aquatic invertebrates and algae) was recorded and the reported acute effect concentrations are all clearly above 1 mg/L. Likewise, the single chronic effect concentration for aquatic algae indicates no chronic effects either (ErC10 > 100 mg/L). Furthermore, the substance is not readily biodegradable but has a low potential for bioaccumulation (log Kow = -4.7). Therefore, the substance is not classified and labelled for environmental hazards, according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.