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EC number: 601-779-5 | CAS number: 121451-02-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Abiotic Degradation by Hydrolysis
The hydrolysis of the test material was investigated in a study conducted in accordance with the standardised guidelines OECD 111, EU Method C.7 and US EPA 161-1 under GLP conditions. The study was assigned a reliability score of 1 in accordance with the principles for assessing data quality as defined in Klimisch et al. (1997).
The rate and route of hydrolysis was studied at pH 5, 7, and 9 using [14C]radiolabelled material. The pseudo first-order rate constant was determined and used to calculate the half-life and DT90 of hydrolysis at pH 9. The second-order rate constant at pH 9 was calculated and used to predict degradation rates at various pH values, and degradates approaching or exceeding 10 % of applied radiocarbon were identified.
The test material was degraded via base-catalysed hydrolysis. Following 7 days of incubation at 50 °C, it was stable to hydrolysis at pH 5 (93.7 % remaining), slightly hydrolysed at pH 7 (78.6 % remaining) and mostly hydrolysed at pH 9 (8.5 % remaining). At 25°C the test material was stable to hydrolysis at pH 5 and 7. At pH 9, the pseudo-first order rate constant of the test material hydrolysis was 0.036 days-1giving half-life and DT90 values of 19 days and 64 days, respectively. The second-order rate constant of hydrolysis was 3600 days-1M-1, giving predicted half-life values of 0.19 days at pH 11 to 1930 days at pH 7. At pH 9, the test material was hydrolysed to form urea, amine, amide, and difluorobenzoic acid forms of the parent material.
Phototransformation in Water
The potential of the test material to undergo photolysis was investigated in a study conducted in accordance with the standardised guidelines with the US EPS 161-2, SETAC-Europe Procedures for Assessing the Environmental Fate and Ecotoxicity of Pesticides, Part 1, Section 10.0 and OPPTS 835.2210 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Under the conditions of this study, the test material photodegraded in buffered water and natural water with a theoretical half-life of 153 and 41 days, respectively, under summer sunlight at 40° N latitude.
Additional information
Abiotic Degradation by Hydrolysis
The hydrolysis of the test material was investigated in a study conducted in accordance with the standardised guidelines OECD 111, EU Method C.7 and US EPA 161-1 under GLP conditions. The study was assigned a reliability score of 1 in accordance with the principles for assessing data quality as defined in Klimisch et al. (1997).
The rate and route of hydrolysis was studied at pH 5, 7, and 9 using [14C]radiolabelled material. The pseudo first-order rate constant was determined and used to calculate the half-life and DT90 of hydrolysis at pH 9. The second-order rate constant at pH 9 was calculated and used to predict degradation rates at various pH values, and degradates approaching or exceeding 10 % of applied radiocarbon were identified.
The test material was degraded via base-catalysed hydrolysis. Following 7 days of incubation at 50 °C, it was stable to hydrolysis at pH 5 (93.7 % remaining), slightly hydrolysed at pH 7 (78.6 % remaining) and mostly hydrolysed at pH 9 (8.5 % remaining). At 25°C the test material was stable to hydrolysis at pH 5 and 7. At pH 9, the pseudo-first order rate constant of the test material hydrolysis was 0.036 days-1giving half-life and DT90 values of 19 days and 64 days, respectively. The second-order rate constant of hydrolysis was 3600 days-1M-1, giving predicted half-life values of 0.19 days at pH 11 to 1930 days at pH 7. At pH 9, the test material was hydrolysed to form urea, amine, amide, and difluorobenzoic acid forms of the parent material.
Phototransformation in Water
The potential of the test material to undergo photolysis was investigated in a study conducted in accordance with the standardised guidelines with the US EPS 161-2, SETAC-Europe Procedures for Assessing the Environmental Fate and Ecotoxicity of Pesticides, Part 1, Section 10.0 and OPPTS 835.2210 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Under the conditions of this study, the test material photodegraded in buffered water and natural water with a theoretical half-life of 153 and 41 days, respectively, under summer sunlight at 40° N latitude.
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