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Diss Factsheets
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EC number: 915-640-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The available aquatic toxicity data from testing with DOWFAX 3B2 were all short-term studies in three species of freshwater fishes and aquatic invertebrates (D. magna). The key parameters for acute toxicity tests with fish and daphnids were 3.7 - 5.0 mg/L (range of 96 -hour LC50 values for fathead minnow, bluegill, and rainbow trout), and 1.5 mg/L (48 -hour EC50 value for D. magna).
Studies with the freshwater algae P. subcapitata were available from testing with category members DOWFAX 2A1 and DOWFAX 8390. For DOWFAX 2A1, a 96 -hour EC50 of 840 mg/L was reported based on cell counts, with a corresponding NOEC of 298 mg/L. In the case of DOWFAX 8390, the 72 -hour EC50 and NOEC values were > 100 mg/L and 10 mg/L, respectively, based on growth rate inhibition.
In addition, long-term aquatic toxicity data for DOWFAX 2A1 and DOWFAX 8390 were available from testing with the freshwater invertebrates. For DOWFAX 2A1 (tested as the equivalent DOWFAX 2EP), the 168 -hour NOEC values for mortality and reproduction of C. dubia were 0.65 mg/L and 1.08 mg/L, respectively. In the case of DOWFAX 8390, the reported 21 -day NOEC values with D. magna were 0.7 mg/L for both mortality and reproduction.
Of these aquatic toxicity values, the NOEC value of 0.65 mg/L for long-term toxicity of DOWFAX 2A1 to the invertebrate C. dubia was the lowest value reported, and this data point was used in the development of PNECaquafor DOWFAX 3B2.
There were activated sludge respiration inhibition studies for analogous structures to DOWFAX 3B2. From these studies, the EC50 value for DOWFAX 8390 in the activated sludge respiration inhibition test was reported as >284 mg/L, and this value was used to set the PNECSTPvalue for DOWFAX 3B2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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