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Diss Factsheets
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EC number: 944-623-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1997
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- None
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 C (Inherent Biodegradability: Modified MITI Test (II))
- Deviations:
- yes
- Remarks:
- Inoculum was run alone instead of in duplicate and the test substance was run in duplicate instead of in triplicate.
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Code number: FAT 92504/A
Batch-No.: 1/95
Purity: 46 %
Appearance: solid blue
Solubility: <0.1 g/l [in water]
Storage: room temperature
Expiration date: 04/1999
ThOD: 1.57 mg 02/mg [ThOD calculated without nitrification] - Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: Mixture of polyvalent bacteria collected from the aration tank of a domestic sewage treatment plant
- Details on inoculum:
- Mixture of polyvalent bacteria collected on May 20, 1997 from the aeration tank of a domestic sewage treatment plant, PRO RHENO Basel communal.
The pH value of the sludge was 7.7. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 7.3 other: mg/ 250 ml test medium
- Based on:
- test mat.
- Initial conc.:
- 7.5 other: mg/ 250 ml test medium
- Based on:
- test mat.
- Initial conc.:
- 7.6 other: mg/ 250 ml test medium
- Based on:
- test mat.
- Initial conc.:
- 47.1 other: mg/30 mg
- Based on:
- ThOD
- Details on study design:
- This method was based on the following conditions:
- test chemicals as sole organic carbon sources
- no pre-adaptation of micro-organisms to the test chemicals
The test was performed in a Voith Sapromat.
Tested chemicals were inoculated in the testing vessels with microorganisms. During the test
period, the Biochemical Oxygen Demand was measured continuousily by means of a BODmeter.
Biodegradability was calculated on the basis of the theoretical oxygen demand (ThOD)
or of the COD, if the ThOD could not be calculated. - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- tested in a concentration of about 167 mg ThOD/100 mg
- Preliminary study:
- None
- Test performance:
- The test was considered valid because:
- the difference of extremes values of the removal of the test chemical at the plateau, at the end of the test or at the end of the 10-d. window was less than 20%. [ 10-d. window: the 10 days immediately following the attainment of 10% biodégradation.]
- the degradation of the reference substance at day 7: >/= 40%
- the degradation of the reference substance at day 14: >/= 65%
- the abiotic degradation of the steril control at day 28 was not: >10% - Key result
- Parameter:
- other: BOD/ThOD
- Value:
- 0
- Remarks on result:
- other: %
- Parameter:
- other: BOD5
- Value:
- 0
- Remarks on result:
- other: mg O2/g
- Key result
- Parameter:
- BOD5*100/ThOD
- Remarks on result:
- other: 0 %
- Parameter:
- BOD5
- Value:
- 0 mg O2/g test mat.
- Results with reference substance:
- Biodegradation of the reference substance after 28 days: 100 %
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- FAT 92504/A was not biodegradable.
- Executive summary:
The inherent biodegradability of FAT 92504/A was determined in a 28 days Modified MITI (II) - Test according to the OECD Guideline for Testing of Chemicals No 302C (adopted 1981).
The test substance and the reference substance were tested in a concentration of about 47.10 mg ThOD/30 mg and 167 mg ThOD/100 mg, respectively.
Results:
Mean value of the biodégradation of FAT 92504/A after 28 days: 0 %
Biodegradation of the reference substance after 28 days: 100 %
The biochemical oxygen demand (BOD5) after 5 days was: 0 mg O2/g
Conclusion:
On the basis of the present study the test substance FAT 92504/A was not biodegradable.
Reference
Reference substance:
The biodégradation of the reference substance corrected by the blank control and measured as BOD versus ThOD was:
92 % after 7 days
97 % after 14 days
100 % after 28 days
Abiotic control:
The abiotic degradation measured as BOD was: 4 % after 28 days
Description of key information
The inherent biodegradability of FAT 92504/A was determined in a 28 days Modified MITI (II) - Test according to the OECD Guideline for Testing of Chemicals No 302C (adopted 1981). Mean value of the biodégradation of FAT 92504/A after 28 days was found to be 0 %. The biochemical oxygen demand (BOD5) after 5 days was 0 mg O2/g. Hence, FAT 92504/A was not biodegradable in this study. The chemical oxygen demand (COD) of FAT 92504/A was assessed according to DIN 38409 - H 41-1 (1980) corresponding to EEC Directive 92 / 69 / C.6. (1992). In this study, the COD of FAT 92504/A was determined to be 666 mg O2/g. Taking the related BOD5 -result of 0 mg O2/g and the COD of 666 mg O2/g into account, the relevant BOD5/COD quotient is <0.5. This indicatesFAT 92504/A should be considered to be not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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