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Diss Factsheets
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EC number: 267-053-1 | CAS number: 67784-78-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
The substance “condensation products of tall-oil fatty acids with diethanolamine and triethanolamine” is a UVCB-substance having variable composition. Therefore, it is not possible to analytically quantify the substance in environmental systems like water, sediment, soil. Accordingly, it also is not possible to experimentally determine absence or presence of a bioaccumulation potential. However, based on the chemical composition, the physical-chemical properties, and the very low toxicological potential as observed in all toxicological and eco-toxicological tests it is very likely that the substance does not have a bioaccumulation potential.
This conclusion is developed in the endpoint summary of Chapter 7.1 “Toxicokinetics” (Section 5.1 of the CSR):
“Based on all available information no final conclusion on a bioaccumulation potential can be drawn. However, based on the physico-chemical properties, the chemical composition and the very low toxicological potential observed in the animal tests the following fate in the animal body is very likely:
1) in an aqueous environment WS400128 forms micelles and thus it may not be available (or only to a small part) for absorption in the digestive tract;
2) the fatty acid esters may be hydrolysed in the digestive tract by digestive enzymes;
3) fatty acid esters that may be absorbed in the digestive tract may be hydrolysed by esterases in the liver (and blood).
The products of hydrolysis, e.g. mono- and diesters of triethanolamine and free fatty acids, are more hydrophilic and thus do not have an accumulation potential.
Therefore, it is rather likely that WS400128 will not bioaccumulate because it is not absorbed in the digestive tract and directly excreted as such and/or it is (partially) hydrolysed to more hydrophilic substances not having an accumulation potential.”
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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