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Diss Factsheets
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EC number: 701-492-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study meets the criteria for Klimisch score 1 because it followed an internationally recognised method (OECD Guideline 301D) and was carried out to Good Laboratory Practice.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- Principles of method if other than guideline:
- not applicable
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Activated sludge bacteria from domestic sewage treatment plant used at about 1 drop sludge filterate inoculum basal medium.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 2 mg/L
- Based on:
- COD
- Parameter followed for biodegradation estimation:
- other: COD
- Details on study design:
- Duplicate test vessels were used for the test substance, positive control and control blank. Test vessels were incubated at 20 ± 1°C.
- Reference substance:
- benzoic acid, sodium salt
- Reference substance:
- aniline
- Preliminary study:
- Not applicable
- Test performance:
- The positive controls were degraded by >60% within 28 days.
- Key result
- Parameter:
- other: COD
- Value:
- 8
- Sampling time:
- 28 d
- Remarks on result:
- other: Additional sampling conducted on days 1, 3, 6, 10, 14 and 21 days.
- Key result
- Parameter:
- COD
- Value:
- 8 g O2/g test mat.
- Results with reference substance:
- Sodium benzoate 97% after 28 days; aniline 61% after 28 days.
- Validity criteria fulfilled:
- yes
- Remarks:
- Both the reference substances achieved greater or equal to 60% degradation, and therefore, the test was valid.
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The substance is not readily biodegradable, achieving 8% degradation over 28 days. The substance is therefore considered to be persistent, but the small amount of biodegradation suggests the substance is not unduly toxic to sewage sludge.
- Executive summary:
A 28 day aerobic ready biodegradability study (to OECD Guideline No. 301D – Closed Bottle Test) was carried out using an analogue of the submission substance (CAS Number 70024-71-4). The effects of the test substance on ready biodegradability were assessed based on the measurement of chemical oxygen demand (COD) using an activated sludge inoculum (from a domestic wastewater plant) that was not pre-adapted to the test substance. Test performance was evaluated using the reference substances sodium benzoate and aniline.
This toxicity study is classified as reliable without restriction (Klimisch Code 1) and satisfies the guideline requirement for biodegradation in water-screening tests.
Results Synopsis
There was only 8.6% degradation of the test substance after 28 days.
There was 97% and 61% degradation of the reference substances sodium benzoate and aniline after 28 days meaning the test was considered valid.
Reference
Description of key information
The ready biodegradability of the substance is considered as a screening study to consider the persistence of the substance in the aquatic environment.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
As an organo-metal salt the substance could never be considered to undergo complete biodegradation to CO2and water. The molecule does, however, include long aliphatic chains that could, in principle, partially degrade abiotically. In fact, several of the studies available demonstrate a small amount of biodegradation that is likely to be attributable to these aliphatic chains. The substance is considered not readily biodegradable.
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