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EC number: 210-871-0 | CAS number: 624-92-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Toxicity studies, carried out according to OECD 216 and 217, give 28-day EC50 greater than 15,000 mg/kg soil dw for soil microorganisms whatever the test considered (nitrogen transformation or carbon transformation). The NOEC = 15,000 mg/kg soil dw can be used as a long term endpoint for PNEC derivation, according to guidance R.7C.
Key value for chemical safety assessment
- Short-term EC50 for soil microorganisms:
- 15 000 mg/kg soil dw
Additional information
In 2007, toxicity of DMDS to soil microorganisms has been investigated by Scheerbaum in two GLP studies.
The first study has been investigated through OECD Guideline 216 and concerned a nitrogen transformation test.
Soil microorganisms were exposed for 28 days to a solution of dimethyl disulfide at different nominal concentrations of 62 - 185 - 556 - 1667 - 5000 and 15000 mg/kg dw.
EC 50 - 28d determined was greater than 15000 mg/kg soil d.w. and NOEC - 28d was of 15000 mg/kg soil d.w.
In this study, DMDS caused only transient effects > 50 % deviation, inhibition as well as stimulation, on day 7 and 14 after application.
Four weeks post application, a slight stimulation > 25 % was found at higher tested concentration (15000 mg/kg soil d.w). Therefore, under normal conditions, DMDS is not expected to lead to any long detrimental effects on nitrogen transformation in soil when applied with maximum 15000 mg/kg DW.
The second study has been investigated through OECD Guideline 217 and concerned a carbon transformation test.
Soil microorganisms were exposed for 28 days to an aqueous solution of dimethyl disulfide TC at different nominal concentrations of 20 - 60 - 180 - 540 - 1620 - 4860 and 14580 mg/kg.
EC 50 - 28d determined was greater than 14580 mg/kg soil d.w.
In this study, DMDS caused only transient effects > 50 % inhibition on the day of application. At the end of the study, DMDS was only found in the highest applied test group.
7 days post application, a slight stimulation was found at higher dosage levels. 4 weeks post application, no effects were detected on glucose induced respiration rates in any dosage level. Therefore, under normal conditions, DMDS is not expected to lead to any long detrimental effects on carbon transformation in soil when applied with maximum 14580 mg/kg dw.
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