Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

The LD50 cut-off of the test item is 200 mg/kg body weight by oral route in the rat. The LD50 is between 50-300 mg/kg bw.

The dermal LD50 of the test item was found to be higher than 2000 mg/kg body weight in male and between 1000 mg/kg body weight and 2000 mg/ kg body weight in female CRL:(WI) rats.

The inhalatory LC50, 4h value of Diformal in Wistar rats was established to be within the range of 0.05 – 0.5 mg/L.

Key value for chemical safety assessment

Additional information

Justification for classification or non-classification

The oral LD50 is between 50-300 mg/kg bw and therefore the test substance is placed in Cat III according to GHS.

The dermal LD50 of the test item was found to be higher than 2000 mg/kg body weight in male and between 1000 mg/kg body weight and 2000 mg/ kg body weight in female CRL:(WI) rats. The test substance is placed in Cat IV according to GHS.

The inhalatory LC50 was established to be within the range of 0.05 – 0.5 mg/L and therefore the test substance is placed in Cat II according to GHS.