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main component 1 (isomer 1): 2-{6-fluoro-4-[3-(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonapht-7-ylamino]-1,3,5-triazin-2-ylamino}-3-{6-fluoro-4-[3-(1,5-disulfonaphth-2-ylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt;main component 1 (isomer 2): 2-{6-fluoro-4-[3-(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-3-{6-fluoro-4-[3-(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt;main component 2: 2,3-bis-{6-fluoro-4-[3-(2,5-disulfo-phenylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt;main component 3: 2,3-bis-{6-fluoro-4-[3-(1,5-disulfonaphth-2-ylazo)-4-hydroxy-2-sulfonaphth-7-ylamino]-1,3,5-triazin-2-ylamino}-propane sodium salt
EC number: 422-610-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 September 1996 to 13 January 1997
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Identity: FAT 40557/A
Batch-no.: PV1
Appearance: Solid powder, red-brown
Expiration date: September, 2002
Storage conditions: At room temperature - Radiolabelling:
- no
- Analytical monitoring:
- yes
- Buffers:
- pH 4.0: Ciba-Geigy Code No. P07: 0.1 mole acetic acid + 0.1 mole sodium acetate diluted to 1000 mL with water + 60.0 mL 1 N HCI.
pH 7.0: Ciba-Geigy Code No. P10: 0.041 mole disodium hydrogen phosphate+ 0.028 mole potassium dihydrogen phosphate diluted to 1000 mL with water.
pH 9.0: Ciba-Geigy Code No. P12: 0.043 mole disodium tetraborate + 0.017 mole potassium dihydrogen phosphate diluted to 1000 mL with water. - Details on test conditions:
- 300.0 to 330.0 mg test substance was dissolved and diluted to 100.0 mL with water. 10 mL of this solution was pipetted into a 100 mL measuring flask, which was then filled up to the mark with the respective buffer solution. The temperature and the pH are checked (pH 4, 7 and 9).
- Duration:
- 2.4 h
- Temp.:
- 50 °C
- Initial conc. measured:
- >= 0.304 - <= 0.317 g/L
- Duration:
- 5 d
- Temp.:
- 50 °C
- Initial conc. measured:
- >= 0.304 - <= 0.317 g/L
- Duration:
- 43.2 h
- pH:
- 4
- Temp.:
- 40 °C
- Initial conc. measured:
- >= 0.303 - <= 0.324 g/L
- Duration:
- 47.5 h
- pH:
- 9
- Temp.:
- 60 °C
- Initial conc. measured:
- >= 0.302 - <= 0.325 g/L
- Duration:
- 92.9 h
- pH:
- 4
- Temp.:
- 25 °C
- Initial conc. measured:
- >= 0.315 - <= 0.319 g/L
- Duration:
- 6.7 h
- pH:
- 9
- Temp.:
- 70 °C
- Initial conc. measured:
- >= 0.309 - <= 0.311 g/L
- Duration:
- 5.9 h
- pH:
- 9
- Temp.:
- 80 °C
- Initial conc. measured:
- >= 0.302 - <= 0.328 g/L
- Number of replicates:
- 2
- Preliminary study:
- After 2.4 h at 50 °C pH 4: 15.1 %; pH 7: 1. 4%; pH 9: 3.9 %
After 5 days at 50 °C pH 4: 100 %; pH 7: 4.2 %; pH 9: 65 %
At 50 °C the test substance FAT 40557/A hydrolyses less than 10 % at pH 7, no further testing at pH 7 is necessary. The hydrolysis of the test substance is examined at pH 4 and 9 . - Transformation products:
- not measured
- pH:
- 4
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 71.3 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 4
- Temp.:
- 40 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 22.3 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 9
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 2 976.4 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: Calculated from other temperatures
- pH:
- 9
- Temp.:
- 60 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 21.9 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 9
- Temp.:
- 70 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 7.7 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 9
- Temp.:
- 80 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 2.1 h
- Type:
- (pseudo-)first order (= half-life)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The test substance has a half-life period of longer than one year at 25 °C and pH 7.
- Executive summary:
In a GLP-compliant hydrolysis test performed according to OECD guideline 111, the stability of the test substace was determined at pH 4, 7, and 9. In a preliminary study, it was determined that the test substance was stable at pH 7 at 50 °C with a calculated half-life period longer than one year at 25 °C and therefore no further testing was performed at pH 7. In two additional tests, it was determined that the the half-life period at 25 °C at pH 4 and 9 was 71.2 hours (3 days) and 2976.4 hours (124 days), respectively.
Reference
Preliminary study:
At 50 °C the test substance FAT 40557/A hydrolyses more than 10 % at pH 4 and pH 9. For this reason, the hydrolysis is examined at pH 4 and pH 9. The test substance is stable at pH 7 at 50 °C; it has a half-life period longer than one year at 25 °C and pH 7. Test 1 and Test 3 must be carried out at pH 4 and pH 9.
Description of key information
The test substance is hydrolytically stable.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 25 °C
Additional information
In a GLP-compliant hydrolysis test performed according to OECD guideline 111, the stability of the test substance was determined at pH 4, 7, and 9 (CG 1997). In a preliminary study, it was determined that the test substance was stable at pH 7 at 50 °C with a calculated half-life period longer than one year at 25 °C and therefore no further testing was performed at pH 7. In two additional tests, it was determined that the half-life period at 25 °C at pH 4 and 9 was 71.2 hours (3 days) and 2976.4 hours (124 days), respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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