Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-808-8 | CAS number: 88-19-7
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only a summary of study results. See "Executive summary" for all details.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 974
- Report date:
- 1974
Materials and methods
Test material
- Reference substance name:
- Toluene-2-sulphonamide
- EC Number:
- 201-808-8
- EC Name:
- Toluene-2-sulphonamide
- Cas Number:
- 88-19-7
- Molecular formula:
- C7H9NO2S
- IUPAC Name:
- 2-methylbenzene-1-sulfonamide
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- LD50 > 7940 mg/kgbw when applied as 50% suspension in corn oil to rabbits.
- Executive summary:
ACUTE DERMAL TOXICITY Species New Zealand Albino Rabbits
LD50 > 7,940 Mg/Kg 95% Confidence Limits - Mg/Kg
Exposure 24 hours
CONDITIONS Applied as a 50.0% suspension in corn oil
Signs of Intoxication: Reduced appetite and activity for one to two days.
Survivors( 14 Days): Viscera appeared normal.
Dose mg/kg Initial bw males Initial bw females Mortalities/doses Males Mortalities/doses Females Mortalities/doses Combined 2000 2.4 - 0/1 - 0/1 5010 2.4 - 0/1 - 0/1 7940 2.3 2.4 0/1 0/1 0/2
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
