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EC number: 279-242-6 | CAS number: 79720-19-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Test organisms (species):
- Cyprinus carpio
- Test type:
- semi-static
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
- Hardness:
- 11,5 °dH
- Test temperature:
- mean = 20 °C
- pH:
- 7.8 to 8.4
- Details on test conditions:
- Test tanks: 20 l
Test volume: 10 l, changed daily
Aeration: continuous in the test tanks
Light/dark cycle: 16/8 h
Density of animals: 10 animals per test tank, each at ~ 1.0 g
Oxygen values during the test: 89 - 100 % saturation - Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.097 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 0.06 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- 0.25 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The LC50 (96 h) was determined to be 0.097 mg/L (range 0.06 mg/l - 0.13 mg/l).
- Executive summary:
The acute fish toxicity of the substance was tested according to OECD Guideline 203 compliant with GLP (RL1; Evonik, 2000). Cyprinus carpio was exposed in a semi-static testing regime (daily medium exchange). Test item analysis (dissolved organic carbon) was performed for the stock solution (0 h and 96 h: the measured concentration of the stock solution after 96 h did not deviate by more than 20% from the freshly prepared solution) as well as for separately incubated stability samples (without fish) for three nominal concentrations (2 mg/L; 5 mg/L; 10 mg/L) after 0 hours and after 24 hours. The recovery rate of the additional concentration batches was more than 80%. The measured values after 24 h did not deviate by more than 20% from the freshly prepared solutions. As such, the test item was assumed to be stable in test medium during the test and all (no)effect concentrations were calculated based on nominal values. The nominal concentrations for the test were calculated based on the analytical value determined for the stock solution after 0 h.
10 fish were used per treatment level: 5 test item concentrations (1.0; 0.5; 0.25; 0.13; 0.06 mg/L) plus one control.
pH value during the test was between 7.8 and 8.4, oxygen saturation levels were between 89% to 100%.
The following (no)effect concentrations were determined:
LC50 (96 h) = 0.097 mg/L (range 0.06 mg/l - 0.13 mg/l);
LC0 (96 h) = 0.06 mg/L;
LC100 (96 h) = 0.25 mg/L.
Reference
Description of key information
In a semistatic test according to OECD 203 with daily renewal, the following (no)effect concentrations were determined for Cyprinus carpio:
LC50 (96 h) = 0.097 mg/L (range 0.06 mg/l - 0.13 mg/l);
LC0 (96 h) = 0.06 mg/L;
LC100 (96 h) = 0.25 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.097 mg/L
Additional information
The acute fish toxicity of the substance was tested according to OECD Guideline 203 compliant with GLP (RL1; Evonik, 2000). Cyprinus carpio was exposed in a semi-static testing regime (daily medium exchange). Test item analysis (dissolved organic carbon) was performed for the stock solution (0 h and 96 h: the measured concentration of the stock solution after 96 h did not deviate by more than 20% from the freshly prepared solution) as well as for separately incubated stability samples (without fish) for three nominal concentrations (2 mg/L; 5 mg/L; 10 mg/L) after 0 hours and after 24 hours. The recovery rate of the additional concentration batches was more than 80%. The measured values after 24 h did not deviate by more than 20% from the freshly prepared solutions. As such, the test item was assumed to be stable in test medium during the test and all (no)effect concentrations were calculated based on nominal values. The nominal concentrations for the test were calculated based on the analytical value determined for the stock solution after 0 h.
10 fish were used per treatment level: 5 test item concentrations (1.0; 0.5; 0.25; 0.13; 0.06 mg/L) plus one control.
pH value during the test was between 7.8 and 8.4, oxygen saturation levels were between 89% to 100%.
The following (no)effect concentrations were determined:
LC50 (96 h) = 0.097 mg/L (range 0.06 mg/l - 0.13 mg/l);
LC0 (96 h) = 0.06 mg/L;
LC100 (96 h) = 0.25 mg/L.
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