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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
March 7 - 11 1988
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP study according to DIN 38412 guideline

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988
Report date:
1988

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: DIN 38412
Deviations:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
3,7-dimethyloct-6-en-1-yn-3-ol
EC Number:
249-482-6
EC Name:
3,7-dimethyloct-6-en-1-yn-3-ol
Cas Number:
29171-20-8
Molecular formula:
C10H16O
IUPAC Name:
3,7-dimethyloct-6-en-1-yn-3-ol
Details on test material:
Purity: 99%

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no
Details on test solutions:
test solutions were prepared in reconstituted freshwater according to DIN 38412 (Draft 1981)
test concentrations (nominal): 10, 21.5, 46.4, 100 mg/L (selected after a range finder test)

Test organisms

Test organisms (species):
Leuciscus idus
Details on test organisms:
Body length: 8.1 cm (range 7.2-9.3)
Body weight: 5.3 g (range 3.6-8.3)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Post exposure observation period:
none

Test conditions

Hardness:
2.5 mmol/L
Test temperature:
20 +/- 1 °C
pH:
about 8.0
Dissolved oxygen:
7.7-9.0 mg/L
Salinity:
294.0 mg/L CaCl2x 2H2O
123.3 mg/L Mg SO4 x 7 H2O
64.8 mg/L NaHCO3
5.8 mg/L KCL
Nominal and measured concentrations:
10.0, 21.4, 46.4, 100 mg/L nominal concentrations
Details on test conditions:
animals per test: 10
loading (g fish/L test water): 5.3
test vessels (all-glass): 30 cm x 22cmx 24cm
volume of water: 10L
withdrawal of food before exposure: 1 day
contineous aeration with oil-free air
determination of mortality: after 1, 4, 24, 48, 72, 96 hours
Reference substance (positive control):
yes
Remarks:
Chloroacetamide

Results and discussion

Effect concentrationsopen allclose all
Duration:
1 h
Dose descriptor:
LC50
Effect conc.:
31.8 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
21.5 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
46.4 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
31.8 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
no mortality in controls,
no other symptoms detectable
Results with reference substance (positive control):
LC 50 after 48h: about 32 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The 96h LC50 of Dehydrolinalool for Golden Orfe (Leuciscus idus L) is 31.8 mg/l.
Executive summary:

The toxicity of Dehydrolinalool to Golden Orfe (Leudiscus Idus L) was determined in a 96-hour static test according to the OECD Guideline DIN 38412. The 96h LC50 was found to be 31.8 mg/l.