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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 217-276-5 | CAS number: 1795-48-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
General information:
Immediately remove any clothing soiled by the product.
Remove breathing equipment only after contaminated clothing have been completely removed.
After inhalation:
Supply fresh air or oxygen; call for doctor.
After skin contact:
Immediately wash with water and soap and rinse thoroughly.
Seek immediate medical advice.
After eye contact:
Rinse opened eye for several minutes under running water.
If symptoms persist, consult a doctor.
After swallowing:
If swallowed, wash out mouth with plenty of water.
Drink plenty of water and provide fresh air.
Call for a doctor immediately.
Important symptoms and effects, both acute and delayed:
No further relevant information available.
Indication of any immediate medical attention and special treatment needed:
No further relevant information available.
Fire-fighting measures
Suitable extinguishing agents:
CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
Use fire extinguishing methods suitable to surrounding conditions.
Special hazards arising from the substance or mixture:
Formation of toxic gases is possible during heating or in case of fire.
Nitrogen oxides (NOx)
Advice for firefighters · Protective equipment:
Wear self-contained respiratory protective device.
Additional information:
Cool endangered receptacles with water spray.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
Accidental release measures
Personal precautions, protective equipment and emergency procedures:
Wear protective equipment.
Keep unprotected persons away.
Keep away from ignition sources.
Environmental precautions:
Do not allow to enter sewers/ surface or ground water.
Methods and material for containment and cleaning up:
Ensure adequate ventilation.
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Do not flush with water or aqueous cleansing agents
Dispose of the material collected according to regulations.
Reference to other sections:
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
Handling and storage
This substance is handled under strictly controlled conditions in accordance with Reach regulation Article 18(4) for transported isolated intermediate. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management system is available at each site. Written confirmation of application of strictly controlled conditions has been received from every downstream user of the intermediate.
Precautions for safe handling:
Ensure good ventilation/exhaustion at the workplace.
Prevent formation of aerosols.
Information about fire - and explosion protection:
Keep ignition sources away - Do not smoke.
Storage:
Store only in the original receptacle.
Further information about storage conditions:
Store in cool, dry conditions in well sealed receptacles.
Keep container tightly sealed.
Storage class: 6.1A (VCI)
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 2483
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Marine transport (UN RTDG/IMDG)
- UN number:
- 2483
Shipping information
- Proper shipping name and description:
- ISOPROPYL ISOCYANATE
- Chemical name:
- Isocyanic acid isopropyl ester
- Labels:
- 6.1+3
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Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 2483
Shipping information
- Proper shipping name and description:
- ISOPROPYL ISOCYANATE
- Chemical name:
- Isocyanic acid isopropyl ester
- Labels:
- 6.1+3
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
This substance is handled under strictly controlled conditions in accordance with Reach regulation Article 18(4) for transported isolated intermediate. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management system is available at each site. Written confirmation of application of strictly controlled conditions has been received from every downstream user of the intermediate.
Personal protective equipment:
General protective and hygienic measures:
The usual precautionary measures are to be adhered to when handling chemicals.
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Do not inhale gases / fumes / aerosols.
Avoid contact with the eyes and skin.
Respiratory protection:
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use self-contained respiratory protective device.
Protection of hands:
Protective gloves
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer.
Penetration time of glove material:
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
Eye protection:
Tightly sealed goggles
Body protection:
Light weight protective clothing
Stability and reactivity
Reactivity:
No further relevant information available.
Chemical stability
Thermal decomposition / conditions to be avoided: To avoid thermal decomposition do not overheat.
Possibility of hazardous reactions:
Reacts violently with water.
Conditions to avoid:
Heating.
Incompatible materials:
Strong oxidizing agents
Acids
Water/Moisture
Strong alkalis
Hazardous decomposition products:
No dangerous decomposition products known.
Additional information:
Sensitive to moisture
Disposal considerations
Must not be disposed together with household garbage.
Do not allow product to reach sewage system.
Uncleaned packaging:
Disposal must be made according to official regulations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.