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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
20 August 2012 to 11 September 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
pour point
Key result
Melting / freezing pt.:
>= 18 - <= 24 °C
Atm. press.:
1 013 hPa
Decomposition:
no
Remarks on result:
other: Determined as pour point.

The pour point was calculated using the equation: P = S + 3

where:

P = pour point (K)

S = stationary point (K)

Conclusions:
The pour point of the substance as a 50% w.w. concentration in pharmaceutical white oil is 21 ± 3°C.
Executive summary:

The pour point of the substance as a 50% w.w. concentration in pharmaceutical white oil is 21 ± 3°C. The pour point was determined in a GLP-compliant pour point test, following OECD guideline 102 (Harlan 2013). The study is considered reliable and relevant for use for this endpoint.

Description of key information

The pour point of the substance as a 50% w.w. concentration in pharmaceutical white oil is 21 ± 3°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
21 °C

Additional information

The pour point was determined in a GLP-compliant pour point test, following OECD guideline 102 (Harlan 2013).