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Physical & Chemical properties

Auto flammability

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Reference
Endpoint:
auto-flammability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
30 September 2012 to 9 October 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.15 (Auto-Ignition Temperature (Liquids and Gases))
Deviations:
yes
Remarks:
Due to instrument failure atmospheric pressure not measured. Historical data used to quote minimum and maximum atmospheric pressure.
GLP compliance:
yes (incl. certificate)
Key result
Auto-ignition temperature:
>= 369 - <= 379 °C
Atm. press.:
>= 95.79 - <= 103.93 kPa
Remarks on result:
other: Atmospheric pressure not measured. Historical data used to quote minimum and maximum atmospheric pressure.
The sample burned with yellow/blue or orange blue flame with grey fumes emitted.
Conclusions:
The substance as a 50% w.w. concentration in pharmaceutical white oil was determined to have a auto-ignition temperature of 374 ± 5°C.
Executive summary:

The substance as a 50% w.w. concentration in pharmaceutical white oil was determined to have an auto-ignition temperature of 374 ± 5°C. The auto-ignition temperature of the test item was tested in a GLP-compliant study following EC 440/2008 A15 method (Harlan 2013). The study is considered reliable with restrictions and relevant for use for this endpoint.

Description of key information

The substance as a 50% w.w. concentration in pharmaceutical white oil was determined to have an auto-ignition temperature of 374 ± 5°C.

Key value for chemical safety assessment

Autoflammability / Self-ignition temperature at 101 325 Pa:
374 °C

Additional information

The auto-ignition temperature of the test item was tested in a GLP-compliant study following EC 440/2008 A15 method (Harlan 2013).