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Physical & Chemical properties

Dissociation constant

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Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14/09/1999 - 15/03/2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP, Guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7370 (Dissociation constants in water)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: EU Annex IIA Point 2.9.4
Deviations:
no
GLP compliance:
yes
Dissociating properties:
yes
No.:
#1
pKa:
12.46
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 11.6; Absorbance at 268 nm = 0.603
No.:
#2
pKa:
12.6
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 11.9; Absorbance at 268 nm = 0.581
No.:
#3
pKa:
12.62
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 12.2; Absorbance at 368 nm = 0.518
No.:
#4
pKa:
12.73
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 12.5; Absorbance at 268 nm = 0.455
No.:
#5
pKa:
12.82
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 12.8; Absorbance at 268 nm = 0.384
Conclusions:
pKa = 12.6
(pH range 11.6 – 12.8)
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
21/08/1995 - 29/07/1998
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP, Guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
Deviations:
no
GLP compliance:
yes
Dissociating properties:
no
Conclusions:
Dinotefuran does not dissociate over the environmentally significant pH range.
No dissociation (pH range 1.4 – 12.3)

Description of key information

Dinotefuran does not dissociate over the environmentally significant pH range. No dissociation (pH range 1.4 – 12.3)

Key value for chemical safety assessment

pKa at 20°C:
12.6

Additional information