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Physical & Chemical properties

Dissociation constant

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Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14/09/1999 - 15/03/2000
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP, Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000
Report Date:
2000

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7370 (Dissociation constants in water)
Deviations:
no
Qualifier:
according to
Guideline:
other: EU Annex IIA Point 2.9.4
Deviations:
no
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: solid

Results and discussion

Dissociating properties:
yes
Dissosciation constantopen allclose all
No.:
#1
pKa:
12.46
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 11.6; Absorbance at 268 nm = 0.603
No.:
#2
pKa:
12.6
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 11.9; Absorbance at 268 nm = 0.581
No.:
#3
pKa:
12.62
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 12.2; Absorbance at 368 nm = 0.518
No.:
#4
pKa:
12.73
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 12.5; Absorbance at 268 nm = 0.455
No.:
#5
pKa:
12.82
Temp.:
20 °C
Remarks on result:
other: Dinotefuran solution pH 12.8; Absorbance at 268 nm = 0.384

Applicant's summary and conclusion

Conclusions:
pKa = 12.6
(pH range 11.6 – 12.8)