Registration Dossier
Registration Dossier
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EC number: 232-235-1 | CAS number: 7790-98-9
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 12 mg/L
Additional information
In a non-standard aquatic semi-static long-term juvenile growth assay conducted in Danio rerio, Ammonium Perchlorate was characterised by 4- and 12-week (chronic) NOECs of 10 mg/L Perchlorate ion for standard endpoints (mortality, growth, general condition, behavior) as well as whole-body T4 levels. The corresponding Ammonium Perchlorate NOEC was 12 mg/L.
The 12-week LOEC was 0.01 mg/L Perchlorate ion for colloidal T4 ring intensity (decreased), a very sensitive marker of T4 depletion. The corresponding Ammonium Perchlorate LOEC was 0.012 mg/L. This effect on a non-required endpoint is not considered for PNEC derivation in absence of effect on whole-body T4 levels and because hormones are not ecotoxicologically considered endpoints.
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