Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 204-442-7 | CAS number: 121-00-6
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- RTECS Number: SL1945000
- Author:
- RTECS Database
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances) : TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 27,15,1985
- Reference Type:
- review article or handbook
- Title:
- Dose No.: B244
- Author:
- RSC Publishing
- Year:
- 2 011
- Bibliographic source:
- Dictionary of Substances and their effects (DOSE); : Toxicol. Lett. 1985, 27, 15.
- Reference Type:
- other: Authoritative data base
- Title:
- HSDB Number : 3913
- Author:
- HSDB Database
- Year:
- 2 011
- Bibliographic source:
- HSDB (Hazardous Substances Data Bank); US national Library of Medicine reviewed by SRC:IARC. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. Available at: http://monographs.iarc.fr/index.php, p. V40 135 (1986)
- Reference Type:
- review article or handbook
- Title:
- DPIM : BQI000
- Author:
- Richard J. Lewis, Sr.
- Year:
- 2 007
- Bibliographic source:
- SAX (Sax's Handbook of Dangerous Industrial Materials) : Toxicology Letters. 27 (1985), 15.
- Reference Type:
- review article or handbook
- Title:
- SciFInder ID : 116
- Author:
- Takahashi, O.
- Year:
- 2 011
- Bibliographic source:
- SciFInder, American Chemical Society (ACS); : Takahashi, O.; Toxicology Letters 1985, V27(1-3), P15-25 CAPLUS
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Data is from RTECS,DOSE,HSDB,SAX,SciFinder database
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-tert-butyl-4-methoxyphenol
- EC Number:
- 204-442-7
- EC Name:
- 2-tert-butyl-4-methoxyphenol
- Cas Number:
- 121-00-6
- Molecular formula:
- C11H16O2
- IUPAC Name:
- 2-tert-butyl-4-methoxyphenol
- Details on test material:
- - Name of test material (as cited in study report): tert-butyl-4-methoxyphenol
- Substance type: Organic
- Physical state: Solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 881 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: Toxic Effect : Blood - hemorrhage
- Mortality:
- Lethal dose ; 50 percent kill
- Clinical signs:
- Toxic Effect : Blood - hemorrhage
Applicant's summary and conclusion
- Conclusions:
- Intraperitoneal toxicity of tert-butyl-4-methoxyphenol to rat was examined at dose concentration of 881 mg/kg of body weight.
- Executive summary:
Intraperitoneal toxicity oftert-butyl-4-methoxyphenolto rat was examined at dose concentration of 881 mg/kg of body weight.
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