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EC number: 231-847-6
CAS number: 7758-98-7
High quality single-species EC50 values and NOEC/(L(E) C10 values are available for 3 freshwater algae species. A chronic Biotic Ligand Model was developed for S. Subcapitata and validated for 3 additional speicies. The NOECs and the chronic algae Biotic ligand models (BLM) are carried forward to the risk characterisation.
High quality chronic single-species NOEC/(L(E) C10 values are available for 4marine algae species. The observed effects are related to the organic carbon content of the test waters. The NOECS and organic carbon relationships are carried forward to the risk characterisation.
Freshwater algae NOECS
High quality chronic NOEC/(L(E) C10 values
are available for 3 species:Chlamydomonas reinhardti, Chlorella
vulgaris and Pseudokirchernella subcapitata.
The NOECs were used to calculate high quality
“species geometric mean” NOEC values for each endpoint and the most
sensitive endpoint for each of the algae species was retained as
"species-mean" NOEC. The "species mean" NOEC value range from 43 µg/l Cu
forPseudokirchernella subcapitata(endpoint growth; n=4) to 138
µg/l Cu forChlorella vulgaris(endpoint growth; n=17). These
values are used for the PNEC derivation.
variability are observed. The effects data-set fromPseudokirchernella
subcapitatawas used for the development of an algae BLM (De
Schamphelaere et al, 2003) The
capacity of the BLM for predicting copper toxicity to other algae
species was demonstrated from copper toxicity studies withChlamydomonas
reinhardtiandChlorella vulgaris(De schamplelaere and Janssen,
Research related to copper acclimation and
deficiency (Bossuyt et al, 2004) demonstrated that, based on the algal
biomass, the growth rate, the pigment diversity and the autotrophic
index, an optimal concentration range was observed between 1 and 35µg
Cu/L. Deficiency was observed at lower levels, toxicity was observed at
Marine algae NOECS
High quality chronic NOEC values are
available for 4 species: 2 diatoms (Phaeodactylum tricornutumandSkeletonema
costatum) and 2 macroalgae (Macrocystis pyriferaandFucus
vesiculosis). Individual NOEC values range between 2.9 µg Cu/L (Phaeodactylum
tricornutum, growth) to 50 µg Cu/L(MacrocystisPyrifera,
High quality “species mean” NOEC values are
derived for the most sensitive
endpoint for each of the 4 species of marine algae. The"species mean"
NOEC value range from 2.9 µg/l Cu for thePhaeodactylum
tricornutumto 11 µg/l forFucus vesiculosis. Large
intra-species variability are observed due differences inDOC.
A relation between the observed NOEC and organic carbon content was
established forFucus vesuculosis.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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