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EC number: 203-804-1
CAS number: 110-80-5
In a subchronic oral study (13 weeks) a NOAEL of 100 µL/kg/day (91.9 mg/kg/day, density 0.919 at 25 °C) was determined. Additionally female rats were administered the test substance during gestation (days 1 to 21) and the hereby obtained NOAEL was 25 µL/kg/day. This value was therefore considered as the overall NOAEL for oral repeated dose toxicity (key data from Stenger et al. 1971);In a subchronic study the toxic potential of the test substance 2-ethoxyethanol has been evaluated via inhalation in rats and rabbits. The animals were treated 6 hours daily for 13 weeks. The derived NOELs were 400 ppm for rats and 100 ppm for rabbits (key data from Barbee et al. 1984).In the lowest dose group (1 mL/day applied dermally) the test substance was teratogenic to offspring. Regarding the mean body weight at day 21 of gestation of the lowest dose group (304 g), the applied dose was 3023 mg/kg/day (key data from Hardin 1982).
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