Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

In vitromutagenetic tests did not reveal any genotoxic effect in six well-conducted tests, two Bacterial Reverse Mutation Assays, twoin vitroMammalian Cell Gene Mutation Tests, and twoin vitroMammalian Chromosome Aberration Tests.

Although neither human data norin vivotests are available, the available data fromin vitrotests support the view that TNPP is a non-genotoxic substance.


Short description of key information:
Not genotoxic.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

This chemical is not classifiable as mutagenic according to the criteria of the European Union.