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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
dermal absorption
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
year of publication: 1989
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondery sources, data cited from reviews, reliability of original publications not assignable

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Toxicological Profile for 3,3'-Dichlorobenzidine (Update).
Author:
Agency for Toxic Substances and Disease Registry (ATSDR)
Year:
1998
Bibliographic source:
U.S. Department of Health and Human Services; Public Health Service.
Report date:
1998
Reference Type:
publication
Title:
3,3'-Dichlorbenzidin (3,3'-Dichlor-biphenyl-4,4'-diyldiamin), BUA-Stoffbericht 30.
Author:
Beratergremium für umweltrelevante Altstoffe (BUA)
Year:
1989
Bibliographic source:
VCH Verlag, Weinheim
Report date:
1989

Materials and methods

Test material

Constituent 1
Reference substance name:
3,3'-dichlorobenzidine
EC Number:
202-109-0
EC Name:
3,3'-dichlorobenzidine
Cas Number:
91-94-1
IUPAC Name:
3,3'-dichlorobiphenyl-4,4'-diamine

Results and discussion

Any other information on results incl. tables

The substance is absorbed after dermal exposure: After application of the radiolabelled test item to the shaved skin of rats for 1, 8, and 24 hours a dermal absorption of 6, 23, and 49%, respectively, was calculated based on the amount of radioactivity remaining at the site of application.

Applicant's summary and conclusion