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Diss Factsheets
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EC number: 222-583-2 | CAS number: 3542-36-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The following information was chosen as the key study for this endpoint:
Hooftman R. N, de Wolf J. M. (2003). Dichlorodioctylstannane (CAS # 3542-36-7): Semi-static acute toxicity test with the crustacean species Daphnia magna. Testing laboratory: TNO, Project Organisation, Ecotoxicology, Utrechtseweg 48, P. O. Box 360, 3700 JA Zeist, The Netherlands. Report no.: 01-2497/02. Owner company: Organotin Environmental Programme (ORTEP) Association Stabilizer Task Force. Report date: 2003-09-15.
Hooftman & de Wolf, 2003, was chosen as the key study based upon the lack of deviations from the test guidelines (OECD guideline 202 and EU Method C.2) and the completeness of reporting. Although other sources of information were available these were considered not to be as reliable as the Hooftman & de Wolf, 2003, study.
Key value for chemical safety assessment
Additional information
The key study was selected on the basis that it was a 48 hour study conducted to the accepted OECD guideline for this endpoint, the study was conducted to GLP and the purity was reported as 99.91%. Due to the low solubility of the registered substance in water testing was conducted using test solutions prepared by the Water Soluble Fraction method. Test solutions with a nominal loading rate of 100mg/l were prepared by adding 2 litres of water to 200mg of test material and stirring mechanically for ca. 16 hours. Test solutions were analysed for test material concentration at 0, 24 and 48 hours. The geometric mean concentration was determined to be 0.28 mg/l, this concentration was above the known water solubility for the registered substance. As no immobilisation was reported in the study only a limit value of > 0.28 mg/l was estimated. It was therefore not possible to use this study for the purposes of classification and labelling.
Heer & Glaser, 1992, did report a definitive result; however this could not be used as the key study due to the use of a vehicle (ethanol) in the study.
Rufli, 1988, did not produce a definitive value due to the poor solubility of the test substance. This study was not performed to GLP and produced a higher EC50 value than the key study and therefore was not selected as a key study.
Steinhäuser et al, 1985, lacked information on methodologies and results and therefore could not be considered reliable enough to use as a key study.
In conclusion, the key acute daphnia 48 hour EC50 value is >0.28 mg/L. This cannot be used to classify the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.