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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1974
Report date:
1974

Materials and methods

Test guideline
Qualifier:
no guideline available
GLP compliance:
no
Remarks:
Study predates GLP
Test type:
other: no data
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
(Z)-hex-3-enyl acetate
EC Number:
222-960-1
EC Name:
(Z)-hex-3-enyl acetate
Cas Number:
3681-71-8
Molecular formula:
C8H14O2
IUPAC Name:
(Z)-hex-3-enyl acetate
Details on test material:
- Name of test material (as cited in study report): RIFM 74-59, cis-3-hexenyl acetate
- Substance type: no data
- Physical state: no data
- Analytical purity: no data
- Impurities (identity and concentrations): no data
- Composition of test material, percentage of components: no data
- Isomers composition: no data
- Purity test date: no data
- Lot/batch No.: no data
- Expiration date of the lot/batch: no data
- Stability under test conditions: no data
- Storage condition of test material: no data
- Other: no data

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Doses:
5 g/kg body weight
No. of animals per sex per dose:
10/ dose
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 other: g/kg
Mortality:
None.
Other findings:
Symptomatology: None

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The test substance was assessed for acute toxicity via the dermal route and was found to have an LD50 of greater than 5 g/kg. As such, the test substance is not considered to be acutely toxic by the dermal route.