Registration Dossier
Registration Dossier
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EC number: 253-326-2 | CAS number: 37052-78-1
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to fish
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other:
- Remarks:
- Predicted model calculations
- Justification for type of information:
- Predicted model calculations
- Qualifier:
- according to guideline
- Guideline:
- other: Estimated data
- Principles of method if other than guideline:
- ECOSAR v1.11
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- other: Fish
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 28 d
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 14.247 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Conclusions:
- Based on the ECOSAR database prediction the NOEC was found to be 14.247 mg/l for 28 days.
- Executive summary:
The long term toxicity on fish was predicted for test substance by using EPI suite ECOSAR version 1.1. On the basis of effects observed in a static freshwater system, the NOEC value for the test substance was estimated to be 14.247 mg/l for fish for 28 days of exposure duration. By considering the NOEC value, it can be concluded that the test chemical can not be considered as toxic to fish at environmentally relevant concentrations and cannot be classified aquatic as per the CLP classification criteria.
Reference
Description of key information
Long term toxicity to fish:
The long term toxicity on fish was predicted for test substance by using EPI suite ECOSAR version 1.1. On the basis of effects observed in a static freshwater system, the NOEC value for the test substance was estimated to be 14.247 mg/l for fish for 28 days of exposure duration. By considering the NOEC value, it can be concluded that the test chemical can not be considered as toxic to fish at environmentally relevant concentrations and cannot be classified aquatic as per the CLP classification criteria.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 14.247 mg/L
Additional information
Long term toxicity to fish:
The long term toxicity on fish was predicted for test substance by using EPI suite ECOSAR version 1.1. On the basis of effects observed in a static freshwater system, the NOEC value for the test substance was estimated to be 14.247 mg/l for fish for 28 days of exposure duration. By considering the NOEC value, it can be concluded that the test chemical can not be considered as toxic to fish at environmentally relevant concentrations and cannot be classified aquatic as per the CLP classification criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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