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EC number: 200-543-5 | CAS number: 62-56-6
Table 1: urinary excretion of dermally applied thiourea by a female rabbit
Volume of catheterized urine
Amount of thiourea excreted per time interval
Amount in % of administered dose (6.5 g)
Rate of urinary excretion of unchanged thiourea
Total 0-24 h
In a study on percutaneous absorption of Thiourea one female rabbit (New Zealand White) was used. A 25% (w/v) solution Thiourea, corresponding to 2 g Thiourea/kg body weight was applied to the trunk of the rabbit. The urine was analysed regarding its Thiourea content. It was shown that 3.76 % of the dermally administered Thiourea was excreted unchanged in the urine within 24 h. This represents the minimum amount of urea percutanously absorbed by the rabbit.
There are no data on possible accumulation of Thiourea in the body. Furthermore the study was only conducted with one animal.
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