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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Environmental fate & pathways

Hydrolysis

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Hydrolysis is a common degradation route in the environment, namely the reaction of a substance with water with a net exchange of the X group with an OH at the reaction centre such that RX + H2O → ROH + HX. Hydrolysis is often dependent upon pH as the reaction is commonly driven by hydrogen or hydroxide ions. Hydrolysis kinetics are usually determined experimentally and should be used to consider the test type and whether parent or degradation product should be tested.

Based on the chemical structure of Fluorescent Brightener 219, predictions under acidic and basic conditions by QSAR Toolbox v. 4.0.0 show hydrolysis products, associated to the opening of the benzoxazole ring.

Literature data also reports hydrolysis of benzoxazole derivatives (Jackson et. al. 1972, Studies in Heterocyclic Chemistry. Part IV. Kinetics and Mechanisms for the Hydrolysis of Benzoxazoles).

However, due to the very low solubility of Fluorescent Brightener 219, i.e. below 1 µg/l at 20 °C and pH 7.3 -7.7, hydrolysis test is difficult to conduct and its relevance is likely to be low as the substance is unlikely to be associated to water in the environment.

Additionally, by the nature of their destination of use, benzoxazoles brightener derivatives are not intended to be readily trasformabile in water as this would imply the rapid destruction of the agent, rendering it unsuitable to the purpose.

On these bases, the test on hydrolysis was considered as not relevant and was not run.