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EC number: 601-471-0 | CAS number: 117309-52-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1 - 30 June 1992
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 C (Inherent Biodegradability: Modified MITI Test (II))
- Version / remarks:
- An update has been made to the OECD Guideline since the publication of the report.
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Test material: NSABZ (2-(Naphthalene-2'-sulphonylamino)-benzoic acid)
Date of receipt: 20 December 1991.
Description: Very light brown powder.
Storage: In original container at room temperature. - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- Inoculum: A mixed population of activated sewage sludge microorganisms.
Source: Activated sewage was prepared by sampling 10 different sites around the UK in accordance with OECD Guideline No. 302C.
Preparation: The mixed sludge was fed daily with a 0.1% synthetic sewage and maintained on a constant aeration at 25 ± 1°C.
Usage rate: Equivalent to 100 mg dry weight/l. - Duration of test (contact time):
- ca. 28 d
- Initial conc.:
- ca. 30 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Duration: 28 days.
Criteria: Oxygen consumption measured by direct manometer reading.
Agitation: By magnetic stirrers.
Temperature: 25 ± 1°C.
Lighting: The test was carried out in darkness.
Observations: Manometer volumes were recorded daily.
Test concentrations: NSABZ: 30 mg/L.
Aniline: 100 mg/L. - Reference substance:
- aniline
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 28
- Sampling time:
- 28 d
- Details on results:
- NSABZ attained 28% degradation after 28 days calculated from oxygen uptake.
Aniline attained 49% biodegradation after 7 days and 75% after 14 days thereby confirming the suitability of the inoculum and culture conditions.
Total organic carbon analysis of the test media at Day 0 and Day 28 showed that aniline attained 97% degradation after 28 days. TOC analysis of NSABZ was not possible due to the insoluble nature of the test material. Similarly a reliable COD value could not be obtained.
For the % Biodegradation calculation a ThOD of 2.05 mg O2/mg was used based on the following approximate values for this polymer:
Molecular formula: C17H13NO4S.
Molecular weight: 327.36 g/mol. - Results with reference substance:
- Aniline attained 49% biodegradation after 7 days and 75% after 14 days thereby confirming the suitability of the inoculum and culture conditions.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- NSABZ attained 28% degradation after 28 days calculated from oxygen uptake (% of ThOD) and so, therefore, cannot be considered as inherently biodegradable under the strict terms and conditions of the OECD Guidelines.
- Executive summary:
The inherent biodegradation of 2-(Naphthalene-2'-sulphonylamino)-benzoic acid (NSABZ) was assessed by modified MITI method (II) (OECD Guideline 302C).
NSABZ attained 28% degradation after 28 days calculated from oxygen uptake (% of ThOD) and so, therefore, cannot be considered as inherently biodegradable under the strict terms and conditions of the OECD Guidelines.
Reference
Description of key information
The inherent biodegradation of 2-(Naphthalene-2'-sulphonylamino)-benzoic acid (NSABZ) was assessed by modified MITI method (II) (OECD Guideline 302C).
NSABZ attained 28% degradation after 28 days calculated from oxygen uptake (% of ThOD) and so, therefore, cannot be considered as inherently biodegradable under the strict terms and conditions of the OECD Guidelines.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
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