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Diss Factsheets
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EC number: 444-960-2 | CAS number: 39148-16-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in soil
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in soil: simulation testing
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Transformation products:
- not measured
Reference
Description of key information
Testing of the biodegradation in soil can be omitted.
Key value for chemical safety assessment
Additional information
According to column 2, Annex IX, of the REACH legislation EC 1907/2006, further biotic degradation testing shall be proposed by the registrant if the chemical safety assessment according to Annex I indicates the need to investigate further the degradation of the substance and its degradation products. Based on the high water solubility of the substance (770 g/L at 20 °C and pH 5), the low log Kow (- 2.5 at 20 °C and a pH of 2.5 – 2.6), and the low vapour pressure of the substance (< 1.0 x 10-5 hPa), water is expected to be the main exposure route for this substance in the environment. In order to assess the potential for abiotic degradation, no studies on the hydrolysis are available for the target substance Fosetyl-sodium (CAS 39148-16-8). Therefore, this endpoint is covered by read-across to the analogous substance Fosetyl-aluminium (CAS 39148-24-8). The source substance Fosetyl-aluminium is a long and widely used fungicide. The target substance is a pre-manufacturing product for the synthesis of Fosetyl-aluminium. The study was conducted according to OECD guideline 111 on the hydrolysis of Fosetyl-aluminium. No hydrolysis of Fosetyl-Al was detected after 5 days at 50 °C in pH 4, 7, and 9 solutions. Fosetyl-Al is therefore considered hydrolytically stable. Based on the results with the source substance Fosetyl-Aluminium (CAS 39148-24-8), the target substance Fosetyl-Sodium (CAS 39148-16-8) is also considered to be hydrolytically stable. Thus, abiotic degradation via hydrolysis can be considered negligible for the dissipation of the target substance from the aquatic environment. In order to assess the potential for biotic degradation of Fosetyl-Sodium, a ready biodegradability test is available according to OECD guideline 301D. The results of the test demonstrated that Fosetyl-Sodium is not readily biodegradable (1% biodegradation after 28 days based on ThOD). However, a second study was conducted according to OECD guideline 302C to test for the inherent biodegradability of the test substance. Based on the results of this study Fosetyl-Sodium was observed as inherently biodegradable (86.9% biodegradation after 28 days based on BOD and > 99.9% biodegradation after 28 days based on residue analysis). Therefore, the target substance is not considered persistent in the environment. Based on the aforementioned results, there is no need indicated for further biodegradation testing of the target substance. Thus, the testing of the biodegradation in soil can be omitted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.