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EC number: 298-842-9 | CAS number: 93839-71-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate
- EC Number:
- 298-842-9
- EC Name:
- 4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate
- Cas Number:
- 93839-71-5
- Molecular formula:
- C13H20N2O.C2H4O2
- IUPAC Name:
- 4-[[(2-aminophenyl)methyl]amino]cyclohexyl acetate
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- 28 d
Results and discussion
% Degradation
- Parameter:
- % degradation (TOC removal)
- Value:
- >= 12
- Sampling time:
- 14 d
- Details on results:
- TOC analysis and theoretical C02 production
The TOC concentration of the 1g NA-872 AMINOACETAT/l solution was 642.4 ± 37.07 ppm.
Based on the TOC concentration the Theoretical CO2 production (ThC02) of the NA-872 AMINOACETAT solution was calculated to be
2.36 mg C02/ml.
The concentration was 37 ml of 1g NA-872 AMINOACETAT/l (A and B) in 2 litres test medium. Hence, the theoretical C02 production following
complete degradation was 87.3 mg per 2 litres for A and B.
The positive control contained 80.3 mg sodium acetate (ThC02= 1.07 mg e02/mg) resulting in a theoretical C02 production following complete
degradation of 85.9 mg per 2 litres.
The toxicity control contained 80.3 mg sodium acetate and 37 ml of 1g NA-872 AMINOACETAT/l in 2 litres of test medium. Hence, the theoretical
C02 production following complete degradation of NA-872 AMINOACETAT plus sodium acetate was 173.2 mg per 2 litres.
The relative degradation values calculated from the measurements performed during the test period revealed 12% degradation of
NA-872 AMINOACETAT in test bottle A and no significant degradation in test bottle B.
Thus, the criterion for ready biodegradability (at least 60% degradation within 10 days of biodegradation exceeding 10%) was not met.
In the toxicity control more than 25% degradation occurred within 14 days (based on ThC02)' Therefore, the test substance was assumed to be not
inhibitory.
Applicant's summary and conclusion
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- In conclusion, NA-872 AMINOACETAT was not readily biodegradable under the conditions of the modified Sturm test presently performed.
- Executive summary:
NA-872 AMINOACETAT was tested for its ready biodegradability in the carbon dioxide (C02) evolution test (modified Sturm test). The study procedure was based on EEC directive 92/69, C.4-C, December 1992, and OECD guideline No. 301 B July 17, 1992. Since calculation of the theoretical TOC value was not possible this value was determined by analysis. Prior to the biodegradation study the TOC concentration of a 1 g NA-872 AMINOACETAT/l solution in milli-Q water was determined. The TOC concentration of the 1 g NA-872 AMINOACETAT/l solution was 642.4 ± 37.07 ppm. Based on the TOC concentration the Theoretical C02 production (ThC02) of the NA-872 AMINOACETAT solution was calculated to be 2.36 mg C02 /ml. In the modified Sturm test 37 ml of the 1 g NA-872 AMINOACETAT/l solution was tested in 2 litres test medium, corresponding to 12 mg TOC/1. The relative degradation values calculated from the measurements performed during the test period revealed 12% degradation of NA-872 AMINOACETAT in test bottle A and no significant degradation in test bottle B. Thus, the criterion for ready biodegradability (at least 60% degradation within 10 days of biodegradation exceeding 10%) was not met. In the toxicity control NA-872 AMINOACETAT was found to be not inhibitory. Since all acceptability criteria prescribed by the protocol were met, this study was considered to be valid. In conclusion, NA-872 AMINOACETAT was not readily biodegradable under the conditions of the modified Sturm test presently performed.
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