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Diss Factsheets
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EC number: 222-321-7 | CAS number: 3425-61-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
There is no test performed with Tert-amyl hydroperoxide. The toxic effects on microorganisms of this substance is read-across from data obtained with1,1,3,3-Tetramethylbutyl hydroperoxide (OECD 209 guideline): EC50-3h = 138 mg/L, EC10-3h = 33 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 138 mg/L
- EC10 or NOEC for microorganisms:
- 33 mg/L
Additional information
There is no test performed with Tert-amyl hydroperoxide. The toxic effects on microorganisms of this substance is read-across from data obtained with1,1,3,3-Tetramethylbutyl hydroperoxide.
In order to predict effects of chemicals in the environment and in biological waste water treatment plants, an activated sludge respiration inhibition test was performed. The toxicity to activated sludge was determined in accordance with OECD Test Guideline 209, and in compliance with the OECD principles of Good Laboratory Practice. The reference substance and test substance were measured on two subsequent days. The test is valid as shown by the EC50 of the reference compound, 3,5- dichlorophenol (8 mg/L), the coefficient of variation of the replicates of the control oxygen uptake rates (2% on first day and 3% on second day) and the average oxygen uptake rate for the control replicates of 15 mg O2/g dry weight/hour on the first day and 26 mg O2/g dry weight/hour on the second day. The oxygen uptake rate on the first day is slightly lower than prescribed. Accurate oxygen uptake rate measurements were very well possible as shown by the very low coefficient of variation. Therefore this is a minor deviation which does not invalidate the test. The toxicity of 1,1,3,3-tetramethylbutyl hydroperoxide to activated sludge was determined at a contact time of 3 hours, using various concentrations of the test substance. The inhibitory effect of 1,1,3,3-tetramethylbutyl hydroperoxide at a particular concentration is expressed as a percentage of the two controls.
The EC50 of 1,1,3,3-tetramethylbutyl hydroperoxide for activated sludge after 3 hours contact time is 138 mg/L with 95% confidence limits of 53 and 327 mg/L. The EC10 of 1,1,3,3-tetramethylbutyl hydroperoxide for activated sludge after 3 hours contact time is 33 mg/L with 95% confidence limits of 4 and 78 mg/L. The EC20 and EC80 are 54 and 349 mg/L, respectively.1,1,3,3-tetramethylbutyl hydroperoxide is therefore considered harmless to activated sludge.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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