Registration Dossier
Registration Dossier
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EC number: 211-525-1 | CAS number: 658-79-7
Endpoint summary
Administrative data
Description of key information
N-glycyl-L-tyrosine dihydrate is a white powder at ambient temperature.
The determination of the melting point of N-glycyl-L-tyrosine is strongly dependent on the method used. Several publications indicate that the dipeptide decomposes in a range of 176 °C - 294 °C. In a study with N-glycyl-L-tyrosine dihydrate, conducted according to OECD guideline 102, the estimated melting point is considered to be in a range between 130 and 150 °C and above a temperature of 175 °C the substance is assumed to decompose.
The density of N-glycyl-L-tyrosine was reported to be 1.348 g/cm³ (Tranter, 1952).
The median particle size was determined in a study according to OECD guideline 110 by the laser diffration method. The study obtained a value of D50 = 10.9 µm for N-glycyl-L-tyrosine dihydrate.
The vapour pressure was determined in a study according to OECD guideline 104. The vapour pressure of N-glycyl-L-tyrosine is < 0.0015 Pa at 20 °C.
The partition coefficient was estimated by QSAR using QSAR prediction using Estimation Programs Interface (EPI) SuiteTM v4.1 (MPBPVP v1.40 and KOWWIN v1.68). The estimated logKow of N-glycyl-L-tyrosine is -0.45.
In a study published by Lapanje, S, Grcar, B, Trtnik, G (1980) the water solubility of N-glycyl-L-tyrosine was reported to be 44.1 g/L at 25 °C.
The flammability of N-glycyl-L-tyrosine was determined in a test according to UN Test for class 4.1 substances. The substance did not meet the GHS criteria for flammability.
Based on the molecular structure of N-glycyl-L-tyrosine testing of surface tension, explosiveness and oxidising properties can be omitted.
Additional information
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