1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonyl fluoride

Water solubility

Administrative data

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

18 June 2001 - 19 June 2001

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Comparable guideline study with acceptable restrictions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2001

Report date:

2001

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

yes

Remarks:

Only preliminary test was conducted. Study was conducted in one step, rather than stepwise procedure.

Type of method:

other: Preliminary test

Test material

Test material information

Constituent 1

Reference substance name:

Perfluoro-1- butanesulfonyl fluoride (PBSF)

IUPAC Name:

Perfluoro-1- butanesulfonyl fluoride (PBSF)

Details on test material:

- Name of test material (as cited in study report :Perfluoro-1- butanesulfonyl fluoride (PBSF)
- Substance type: Single-component substance
- Physical state: Clear liquid
- Density: 1.7 g/mL
- Analytical purity: 98%
- Lot/batch no. TCR-00017-096
- Expiration date of the lot/batch: 01-01-2010
- Storage condition of test material: Frozen

Results and discussion

Water solubility

Water solubility:

< 274 µg/L

Temp.:

22 °C

Details on results:

The solubility screen test estimated the solubility of PBSF to be less than 274 ng/mL in water at 22 - 24 °C.

Calculation:
1.0 uL PBSF = 1.0 uL x 1.7 g/mL = 17 mg PBSF
Approximate solubility = 17 mg/6.205 L = 0.27397 mg/L = 274 ug/L = 274 ng/mL

Any other information on results incl. tables

pH not reported

Applicant's summary and conclusion

Conclusions:

Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The solubility screen test estimated the solubility of PBSF to be less than 274 ng/mL in water at 22 - 24 °C.

Executive summary:

The water solubility of PBSF was performed according to 3M Laboratory Method ETS-8-170.1 "Solubility Screen Test: Approximate Solubility Determination of a Test Substance in Various Solvents". The test is equivalent to OECD TG105, preliminary test. This method is a pre-requisite to the shake flask and column elution methods and provides an estimate of the water solubility of the test substance. A 1 uL aliquot of PBSF was introduced into a volumetric flask containing 6.205 L of water. Following sample addition, the volumetric flask was shaken, allowed to settle overnight, and visually observed for PBSF droplets on the bottom of the flask. The solubility screen test estimated the solubility of PBSF to be less than 274 ng/mL in water at 22 - 24 °C.

This study is classified as reliable with restrictions. While the test method is equivalent to OECD TG105 preliminary test, test method is a screen test, no further test was conducted.