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EC number: 205-286-2 | CAS number: 137-26-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
NOEC (28 d, nitrate formation rate): ≥ 31.71 mg a.i./kg soil dw (nominal, OECD 216, soil)
NOEC (28 d, short-term respiration): ≥ 31.71 mg a.i./kg soil dw (nominal, OECD 217, soil)
Key value for chemical safety assessment
Additional information
Two key studies and one supporting study on the toxicity of tetramethylthiuram disulfide (CAS No. 137-26-8) to soil microorganisms are available.
The available key studies (2010) on the toxicity of tetramethylthiuram disulfide (CAS No. 137-26-8) to soil microorganisms were performed according to the OECD Guidelines No. 216 (nitrogen transformation rate, GLP) and 217 (carbon transformation rate, GLP). For these studies agricultural soil was treated with 0 (control and solvent control), 12.69 and 31.71 mg a.i./kg soil dry weight (dw) and incubated for 28 d (carbon transformation) and 70 d (nitrogen transformation). During the incubation period, short-term respiration and nitrate formation of soil subsamples were measured at 0, 7, 14, 28 d after application. Furthermore, nitrate formation of the soil microorganisms was additionally measured at 42, 56, 70 d after application. The test item had no impact on nitrogen transformation (28 days after applications) or soil respiration (28 days after applications) of soil microorganisms when applied at 12.69 mg and 31.7 mg test item/kg soil dry weight treatment.
The key results are supported by the results of a further study (2000), which was performed with the product Thiram 80 WG. This study was conducted according to the BBA-Guideline for the Official Testing of Pesticides, Part VI, 1-1 (1990), under GLP conditions. Thiram 80 WG was applied to two different soil types and incubated for 90 days (soil 1, nitrogen turnover) and 28 days (soil 2, short-term respiration), and the effects on soil microflora activity was recorded. At test termination, no significant effects on short-term respiration and nitrogen turnover were detected, not even at the highest concentration tested, resulting in a 28 d and 90 d NOEC of ≥ 32.48 mg a.i./kg soil dw (nominal), respectively.
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