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EC number: 931-292-6 | CAS number: 308062-28-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Fish: Iwan GR et al (1975) exposed Fathead minnow (Pimephales promelas) to C12-14 AO under static conditions for 96 hours. The LC50 (96 h) based on nominal concentrations of amine oxide ranged from 2.67 to 3.46 mg AO/L depending on the source and pH of the water used.
In a full life-cycle toxicity test (similar to EPA OPPTS 850.1500) fathead minnows (Pimephales promelas) were exposed to C12 -14 AO for 302 days under flow through conditions [Aquatic Environmental Services (1976) ]. The NOEC was 0.42 mg AO/L (mean measured concentration), based on reduced fry survival, reduced egg hatch, and occluded eyes in test fish.
Daphnia: The acute immobilisation (EC50) of C12-14 AO to Daphnia magna was determined according to OECD TG 202 and EC method C.2 under static conditions over a duration of 48 h [Noack M (2001)]. The 48 h EC50 value, based on nominal test concentrations, was 3.1 mg AO/L
A 21-day survival and reproduction test with Daphnia magna following OECD TG 211 is available for C12-14 AO [Maki (1997)]. The 21 -day NOEC was 0.70 mg AO/L, based on both survival and reproduction.
Algae: Ginkel & Kroon (1990) exposed Pseudokirchnerella subcapitata to C12-14 AO under static conditions for 72 hours according to OECD TG 201. The ErC50 (72 h) was 0.266 mg AO/L. The ErC50 (72 h) based on the geometric mean of the four studies available with this species is 0.143 mg AO/L
The toxicity of C12-14 AO to algae was evaluated in a 28 -day freshwater periphyton microcosm assay [Belanger (1999)]. The No-Observed Effect Concentration (NOEC) of the substance to the periphyton community was determined to be >67 ug AO/L, the highest test concentration evaluated (mean measured concentration).
Microorganisms: Kolvenbach (1990) exposed Pseudomonas putida to C12 -14 AO for 18 hours in a Bringmann-Kohn test. The EC10, based on reduction in growth rate, was 24 mg AO/L.
Sediment-dwelling organisms: No studies are available, however risk characterisation using the equilibrium partitioning method indicates that the risk to sediment dwelling organisms is adequately controlled and there is no need for further refinement of the assessment through testing.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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